Tapasin enhances the loading and editing of peptide 'cargo' onto major histocompatibility complex class I molecules, yet it cannot do so alone. Two new reports show that the oxidoreductase ERp57 assists tapasin in these activities.
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Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USAYale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
Panter, Michaela S.
Jain, Ankur
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Univ Illinois, Ctr Biophys & Computat Biol, Urbana, IL 61801 USA
Univ Illinois, Inst Genom Biol, Urbana, IL 61801 USAYale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
Jain, Ankur
Leonhardt, Ralf M.
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Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USAYale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
Leonhardt, Ralf M.
Ha, Taekjip
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Univ Illinois, Ctr Biophys & Computat Biol, Urbana, IL 61801 USA
Univ Illinois, Inst Genom Biol, Urbana, IL 61801 USA
Univ Illinois, Howard Hughes Med Inst, Urbana, IL 61801 USAYale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
Ha, Taekjip
Cresswell, Peter
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Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USAYale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA