Polyacrylates of noble metals as potential antitumor drugs

被引：0
|
作者：
Ostrovskaya L.A. [1 ]
Voronkov M.G. [2 ]
Korman D.B. [1 ]
Bluhterova N.V. [1 ]
Fomina M.M. [1 ]
Rikova V.A. [1 ]
Abzaeva K.A. [2 ]
Zhilitskaya L.V. [2 ]
机构：
[1] Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow
[2] Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk
来源：
Biophysics | 2014年 / 59卷 / 4期
关键词：
experimental antitumor chemotherapy; polyacrylates of noble metals; transplantable murine tumor models;
D O I：
10.1134/S0006350914040216
中图分类号：
学科分类号：
摘要：
The antitumor activity of polyacrylates of the noble metals containing argentum (argacryl), aurum (auracryl) and platinum (platacryl) has been studied using experimental murine solid tumor models (Lewis lung carcinoma and Acatol adenocarcinoma). It has been found that polyacrylates of the noble metals are capable of inhibiting tumor development by 50–90% compared to control. Auracryl that inhibits the growth of Lewis lung carcinoma and Acatol adenocarcinoma by 80 and 90%, respectively, compared to control is the most efficient among the tested compounds and can be recommended for the further profound preclinical studies. © 2014, Pleiades Publishing, Inc.
引用
收藏
页码：642 / 645
页数：3
相关论文
共 50 条
  • [41] Noble metals in polyoxometalates
    Tahmasebi, Morteza
    Mirzaei, Masoud
    Frontera, Antonio
    INORGANICA CHIMICA ACTA, 2021, 523
  • [42] PIEZOREFLECTIVITY OF NOBLE METALS
    GARFINKE.M
    TIEMANN, JJ
    ENGELER, WE
    PHYSICAL REVIEW, 1966, 148 (02): : 695 - &
  • [43] Noble metals potential of sulfide-saturated melts from the subcontinental lithosphere
    Kamenetsky, Vadim S.
    Maas, Roland
    Fonseca, Raul O. C.
    Ballhaus, Chris
    Heuser, Alexander
    Brauns, Michael
    Norman, Marc D.
    Woodhead, Jon D.
    Rodemann, Thomas
    Kuzmin, Dmitri V.
    Bonatti, Enrico
    GEOLOGY, 2013, 41 (05) : 575 - 578
  • [44] Image potential eigenstates and resonances on the (110) surfaces of noble metals: Energies and lifetimes
    S. S. Tsirkin
    E. V. Chulkov
    Journal of Experimental and Theoretical Physics, 2014, 118 : 167 - 175
  • [45] Image Potential Eigenstates and Resonances on the (110) Surfaces of Noble Metals: Energies and Lifetimes
    Tsirkin, S. S.
    Chulkov, E. V.
    JOURNAL OF EXPERIMENTAL AND THEORETICAL PHYSICS, 2014, 118 (02) : 167 - 175
  • [46] USE OF CENTRAL PAIR POTENTIAL IN LATTICE-DYNAMICS OF NOBLE-METALS
    RATHORE, RPS
    VERMA, MP
    INDIAN JOURNAL OF PURE & APPLIED PHYSICS, 1977, 15 (01) : 54 - 55
  • [47] SYNTHESIS OF 9,10-ANTHRAQUINONE MONOALKYLAMINOALKYLHYDRAZONES AS POTENTIAL ANTITUMOR DRUGS
    ANTONINI, I
    POLUCCI, P
    COLA, D
    PALMIERI, G
    MARTELLI, S
    BONTEMPSGRACZ, M
    FARMACO, 1993, 48 (12): : 1641 - 1648
  • [48] Synthesis and biological evaluation of new asymmetrical bisintercalators as potential antitumor drugs
    Antonini, Ippolito
    Santoni, Giorgio
    Lucciarini, Roberta
    Amantini, Consuelo
    Sparapani, Silvia
    Magnano, Amelia
    JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (24) : 7198 - 7207
  • [49] NITRO ANALOGS OF CHLORAMBUCIL AS POTENTIAL HYPOXIA-SELECTIVE ANTITUMOR DRUGS
    PALMER, BD
    WILSON, WR
    DENNY, WA
    ANTI-CANCER DRUG DESIGN, 1990, 5 (04): : 337 - 349
  • [50] Revisiting potential value of antitumor drugs in the treatment of COVID-19
    Zheng, Wenfang
    Zeng, Zekun
    Lin, Shumei
    Hou, Peng
    CELL AND BIOSCIENCE, 2022, 12 (01):
12345