Studien zur Chemie von thienoanellierten O,N- und S,N-haltigen Heterocyclen, 15. Mitt. [1]: Zugänge zum Thieno[3,2-b][1,4]-oxazin-, Thieno[3,2-b][1,4]thiazin-und Thienodithiazepin-GrundgerüstStudies on the Chemistry of Thienoannelated O,N- and S,N-Containing Heterocycles XV [1]: An Access to the Thieno [3,2-b][1,4]oxazine, Thieno [3,2-b][1,4]thiazine and Thienodithiazepine Ring System

被引：0
|
作者：
Thomas Erker
机构：
[1] Institut für Pharmazeutische Chemie der Universität Wien,
[2] A-1090 Wien,undefined
来源：
Monatshefte für Chemie / Chemical Monthly | 1998年 / 129卷 / 6-7期
关键词：
Keywords. 3-Bromo-2-nitrothiophene; Nitro group reduction; Thieno [3; 2-b][1; 4]oxazine; Thieno[3; 2-b][1; 4]thiazine; Thienodithiazepine.;
D O I：
10.1007/PL00013477
中图分类号：
学科分类号：
摘要：
 3-Bromo-2-nitrothiophene is reacted with bifunctional reagents like methyl 3-mercaptopropionate to yield the corresponding thioether derivatives. Reduction of the nitro function followed by ring closure provides a possibility to synthesize the hitherto unknown thieno [3,2-b][1,4]oxazines as well as thieno [3,2-b][1,4]thiazines. In a similar manner, the new thienodithiazepine ring system is obtained.
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页码：679 / 687
页数：8
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