Moving in mysterious ways

被引:0
|
作者
Alison M. Condliffe
Phillip T. Hawkins
机构
[1] Addenbrookes and Papworth Hospitals,Department of Medicine University of Cambridge Clinical Medical School
来源
Nature | 2000年 / 404卷
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摘要
Certain white blood cells home in on pathogens attacking the body by following gradients of chemoattractant to their targets. Cell movement in this chemotactic process requires extension of the cell's leading edge. That, it now emerges, stems from generation of lipid signals by an enzyme called phosphoinositide-3-OH kinase. The result is a highly polarized signalling cascade which leads to directed movement.
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页码:135 / 137
页数:2
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