Fibroblast growth factor 9 delivery during angiogenesis produces durable, vasoresponsive microvessels wrapped by smooth muscle cells

被引：0

作者：

Matthew J Frontini

Zengxuan Nong

Robert Gros

Maria Drangova

Caroline O'Neil

Mona N Rahman

Oula Akawi

Hao Yin

Christopher G Ellis

J Geoffrey Pickering

机构：

[1] Robarts Research Institute,Department of Medicine (Cardiology)

[2] Schulich School of Medicine and Dentistry,Department of Biochemistry

[3] University of Western Ontario,Department of Medical Biophysics

[4] London,Department of Physiology and Pharmacology

[5] Canada and London Health Sciences Centre,undefined

[6] Schulich School of Medicine and Dentistry,undefined

[7] University of Western Ontario,undefined

[8] Schulich School of Medicine and Dentistry,undefined

[9] University of Western Ontario,undefined

[10] Schulich School of Medicine and Dentistry,undefined

[11] University of Western Ontario,undefined

[12] Schulich School of Medicine and Dentistry,undefined

[13] University of Western Ontario,undefined

来源：

Nature Biotechnology | 2011年 / 29卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Frontini et al. propose to improve therapeutic angiogenesis by targeting perivascular smooth muscle cells rather than endothelial cells. They show that FGF9 causes smooth muscle cells to wrap around nascent endothelial tubes, generating blood vessels that are longer lasting and vasoreactive.

引用

页码：421 / 427

页数：6

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