DNA methylation dynamics in health and disease

被引：0
|
作者：
Yehudit Bergman
Howard Cedar
机构：
[1] Institute for Medical Research Israel–Canada,Department of Developmental Biology and Cancer Research
[2] Hebrew University Medical School,undefined
来源：
Nature Structural & Molecular Biology | 2013年 / 20卷
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摘要：
DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established at the time of implantation. In this Review, dynamics of DNA methylation during normal development in vivo are discussed, starting from fertilization through embryogenesis and postnatal growth, as well as abnormal methylation changes that occur in cancer.
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页码：274 / 281
页数：7
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