Hypolipidemic Lactone Derivatives from Highland Barley Monascus

被引：0
|
作者：
Rongrui Wei
Qinge Ma
机构：
[1] Jiangxi University of Traditional Chinese Medicine,Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine, Key Laboratory of Modern Preparation of TCM of Ministry of Education
来源：
Chemistry of Natural Compounds | 2020年 / 56卷
关键词：
highland barley ; lactone derivative; hypolipidemic activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new lactone, named 9-allyl-5-methyl-1H-difuro-isochromene-1,8-dione (1), together with nine known lactone derivatives (2–10), was isolated from highland barley Monascus for the first time. Compounds 1–10 were studied by spectroscopic methods and comparison with references and evaluated for their hypolipidemic activities by measuring the triglyceride content in HepG2 cells with simvastatin as positive control. Among them, compounds 1 and 7 (10 μM) exhibited moderate hypolipidemic activities.
引用
收藏
页码：607 / 610
页数：3
相关论文
共 50 条
  • [1] Hypolipidemic Activity of Monacolin Derivatives from the Highland Barley Monascus purpureus
    Rongrui Wei
    Qinge Ma
    Wei Jiang
    Guoyue Zhong
    Zhipei Sang
    [J]. Chemistry of Natural Compounds, 2020, 56 : 1072 - 1075
  • [2] Hypolipidemic Activity of Monacolin Derivatives from the Highland Barley Monascus purpureus
    Wei, Rongrui
    Ma, Qinge
    Jiang, Wei
    Zhong, Guoyue
    Sang, Zhipei
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2020, 56 (06) : 1072 - 1075
  • [3] Hypolipidemic Lactone Derivatives from Highland BarleyMonascus
    Wei, Rongrui
    Ma, Qinge
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2020, 56 (04) : 607 - 610
  • [4] Structurally diverse Monascus pigments with hypolipidemic and hepatoprotective activities from highland barley Monascus
    Wei, Rong-Rui
    He, Mao-Hua
    Sang, Zhi-Pei
    Dong, Jiang-Hong
    Ma, Qin-Ge
    [J]. FITOTERAPIA, 2022, 156
  • [5] Hepatoprotective Phenylpropanoid Glycosides from Highland Barley Monascus purpureus
    Rongrui Wei
    Qinyuan Wang
    Qingyuan Lin
    Xianbao Jiang
    Zhongli Zhang
    Lan Cao
    Jiazeng Guo
    Qinge Ma
    [J]. Chemistry of Natural Compounds, 2024, 60 : 45 - 49
  • [6] Hepatoprotective Phenylpropanoid Glycosides from Highland Barley Monascus purpureus
    Wei, Rongrui
    Wang, Qinyuan
    Lin, Qingyuan
    Jiang, Xianbao
    Zhang, Zhongli
    Cao, Lan
    Guo, Jiazeng
    Ma, Qinge
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2024, 60 (01) : 45 - 49
  • [7] Analysis of the differences in the chemical composition of monascus rice and highland barley monascus
    Chen, Jia
    Zheng, Qi
    Zheng, Zhenxing
    Li, Yirou
    Liao, Hailang
    Zhao, Hui
    Guo, Dale
    Ma, Yuntong
    [J]. FOOD & FUNCTION, 2022, 13 (13) : 7000 - 7019
  • [8] Hypoglycemic and Hypolipidemic Effect of Germinated Highland Barley
    Li T.
    Du Y.
    Chen Z.
    Zhou W.
    Tu Z.
    Li J.
    [J]. Journal of Chinese Institute of Food Science and Technology, 2022, 22 (09) : 114 - 122
  • [9] Ethnopharmacology, Phytochemistry, and Pharmacology of Highland Barley Monascus purpureus Went: A Comprehensive Review
    Zhu, Mei-Ning
    Wu, Guang
    Chen, Jie
    Qiu, Yong-Wei
    Zhu, Cai-Qing
    Wu, Yong-Zhong
    Ma, Qin-Ge
    Zhong, Guo-Yue
    Wei, Rong-Rui
    [J]. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023, 26 (06) : 1083 - 1092
  • [10] Development of Monascus fermentation technology for high hypolipidemic effect
    Chun-Lin Lee
    Tzu-Ming Pan
    [J]. Applied Microbiology and Biotechnology, 2012, 94 : 1449 - 1459
12345