Hepatoprotective Phenylpropanoid Glycosides from Highland Barley Monascus purpureus

被引：0

作者：

Wei, Rongrui ^{[1
]}

Wang, Qinyuan ^{[1
]}

Lin, Qingyuan ^{[1
]}

Jiang, Xianbao ^{[1
]}

Zhang, Zhongli ^{[1
]}

Cao, Lan ^{[1
]}

Guo, Jiazeng ^{[2
]}

Ma, Qinge ^{[1
]}

机构：

[1] Jiangxi Univ Tradit Chinese Med, Key Lab Modern Preparat Tradit Chinese Med, Res Ctr Nat Resources Chinese Med Mat & Ethn Med, Minist Educ,Personnel Div,Coll Pharm, Nanchang 330004, Peoples R China

[2] Nanyang Normal Univ, Coll Jewelry & Jade Carving, Nanyang 473061, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2024年 / 60卷 / 01期

基金：

中国国家自然科学基金;

关键词：

highland barley Monascus purpureus Went; phenylpropanoid glycoside; hepatoprotective;

D O I：

10.1007/s10600-024-04250-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new phenylpropanoid glycoside, named 4-O-beta-D-glucopyranosyl-7-phenyl-9-propenyl ketone-9-O-beta-Dglucopyranosyl-(6"-> l")-6"-O-alpha-L-rhamnopyranose (1), and four known phenylpropanoid glycosides 2-5 were isolated from highland barley Monascus purpureus Went for the first time. Their structures were determined by their comprehensive spectral data and reported references. Compounds 1-5 were evaluated for their hepatoprotective activities against D-galactosamine-induced toxicity in WB-F344 cells with bicyclol as positive control. As a result, compounds 1 and 2 exhibited moderate hepatoprotective activities.

引用

页码：45 / 49

页数：5

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