Hepatoprotective Phenylpropanoid Glycosides from Highland Barley Monascus purpureus

被引:0
|
作者
Wei, Rongrui [1 ]
Wang, Qinyuan [1 ]
Lin, Qingyuan [1 ]
Jiang, Xianbao [1 ]
Zhang, Zhongli [1 ]
Cao, Lan [1 ]
Guo, Jiazeng [2 ]
Ma, Qinge [1 ]
机构
[1] Jiangxi Univ Tradit Chinese Med, Key Lab Modern Preparat Tradit Chinese Med, Res Ctr Nat Resources Chinese Med Mat & Ethn Med, Minist Educ,Personnel Div,Coll Pharm, Nanchang 330004, Peoples R China
[2] Nanyang Normal Univ, Coll Jewelry & Jade Carving, Nanyang 473061, Peoples R China
基金
中国国家自然科学基金;
关键词
highland barley Monascus purpureus Went; phenylpropanoid glycoside; hepatoprotective;
D O I
10.1007/s10600-024-04250-5
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new phenylpropanoid glycoside, named 4-O-beta-D-glucopyranosyl-7-phenyl-9-propenyl ketone-9-O-beta-Dglucopyranosyl-(6"-> l")-6"-O-alpha-L-rhamnopyranose (1), and four known phenylpropanoid glycosides 2-5 were isolated from highland barley Monascus purpureus Went for the first time. Their structures were determined by their comprehensive spectral data and reported references. Compounds 1-5 were evaluated for their hepatoprotective activities against D-galactosamine-induced toxicity in WB-F344 cells with bicyclol as positive control. As a result, compounds 1 and 2 exhibited moderate hepatoprotective activities.
引用
收藏
页码:45 / 49
页数:5
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