Hypolipidemic Lactone Derivatives from Highland Barley Monascus

被引：0
|
作者：
Rongrui Wei
Qinge Ma
机构：
[1] Jiangxi University of Traditional Chinese Medicine,Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine, Key Laboratory of Modern Preparation of TCM of Ministry of Education
来源：
Chemistry of Natural Compounds | 2020年 / 56卷
关键词：
highland barley ; lactone derivative; hypolipidemic activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new lactone, named 9-allyl-5-methyl-1H-difuro-isochromene-1,8-dione (1), together with nine known lactone derivatives (2–10), was isolated from highland barley Monascus for the first time. Compounds 1–10 were studied by spectroscopic methods and comparison with references and evaluated for their hypolipidemic activities by measuring the triglyceride content in HepG2 cells with simvastatin as positive control. Among them, compounds 1 and 7 (10 μM) exhibited moderate hypolipidemic activities.
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页码：607 / 610
页数：3
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