Genetic polymorphism of glutathione S-transferase P1 gene and lung cancer risk

被引：0
|
作者：
Jordi To-Figueras
Manel Gené
Jesús Gómez-catalán
Esther Piqué
Natividad Borrego
Josep Lluís Carrasco
Josep Ramón
Jacint Corbella
机构：
[1] University of Barcelona,Toxicology Unit, IDIBAPS [Institut d'Investigacions Biomèdiques August Pi i Sunye
[2] University of Barcelona,Department of Public Health
来源：
Cancer Causes & Control | 1999年 / 10卷
关键词：
GSTM1; GSTP1; GSTT1; lung cancer; polymorphisms; susceptibility;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objectives: The human GSTTP1 gene is polymorphic with an A → G transition in exon 5 causing a replacement 105 Ile→Val in the GSTP1 protein. The two isoforms, encoded by the alleles GSTP1*A and GSTP1*B, respectively, show different catalytic efficiencies towards some carcinogenic epoxides. In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility.
引用
收藏
页码：65 / 70
页数：5
相关论文
共 50 条
  • [31] Polymorphisms of the glutathione S-transferase P1 gene and head and neck cancer susceptibility
    Ophuis, MBO
    Roelofs, HMJ
    van den Brandt, PA
    Peters, WHM
    Mann, JJ
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2003, 25 (01): : 37 - 43
  • [32] ATAAA repeat upstream of glutathione S-transferase P1 and prostate cancer risk
    Platz, EA
    Krithivas, K
    Kantoff, PW
    Stampfer, MJ
    Giovannucci, E
    UROLOGY, 2002, 59 (01) : 159 - 164
  • [33] Glutathione S-transferase P1 Genetic Polymorphism, Body Mass Index, and Choice Reaction Time
    Liu, Tao
    Bo, Weihong
    Sun, Xuechuan
    INTERNATIONAL JOURNAL OF OBESITY, 2011, 35 : S31 - S32
  • [34] MicroRNA Regulating Glutathione S-Transferase P1 in Prostate Cancer
    Singh S.
    Shukla G.C.
    Gupta S.
    Current Pharmacology Reports, 2015, 1 (2) : 79 - 88
  • [35] A systemic review of glutathione S-transferase P1 Ile105Val polymorphism and colorectal cancer risk
    Song, Qi-Bin
    Wang, Qi
    Hu, Wei-Guo
    CHINESE JOURNAL OF CANCER RESEARCH, 2014, 26 (03) : 255 - 267
  • [36] Influence Of Air Pollutants And Glutathione S-Transferase P1 Gene Polymorphism In Patients With Bronchial Asthma
    Sada, M.
    Wada, H.
    Inui, T.
    Nakamoto, K.
    Honda, K.
    Nakamura, M.
    Horie, M.
    Mikami, Y.
    Noguchi, S.
    Yamauchi, Y.
    Takizawa, H.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191
  • [37] A systemic review of glutathione S-transferase P1 Ile105Val polymorphism and colorectal cancer risk
    Qi-Bin Song
    Qi Wang
    Wei-Guo Hu
    Chinese Journal of Cancer Research, 2014, 26 (03) : 255 - 267
  • [38] Genetic Polymorphisms of Glutathione S-Transferase P1 and Bladder Cancer Susceptibility in a Chinese Population
    Zhang, RongGui
    Xu, GuangYong
    Chen, WenJun
    Zhang, WeiLi
    GENETIC TESTING AND MOLECULAR BIOMARKERS, 2011, 15 (1-2) : 85 - 88
  • [39] Association of genetic polymorphism of glutathione S-transferase M1,T1, P1 and susceptibility to bladder cancer
    Srivastava, DSL
    Mishra, DK
    Mandhani, A
    Mittal, B
    Kumar, A
    Mittal, RD
    EUROPEAN UROLOGY, 2005, 48 (02) : 339 - 344
  • [40] Lack of association between glutathione S-transferase P1 polymorphism and COPD in Koreans
    Yim, JJ
    Yoo, CG
    Lee, CT
    Kim, YW
    Han, SK
    Shim, YS
    LUNG, 2002, 180 (02) : 119 - 125
12345