Validation of a colorimetric method for determination of paracetamol in exhaled breath condensate

被引：0
|
作者：
Fariba Pourkarim
Elaheh Rahimpour
Maryam Khoubnasabjafari
Vahid Jouyban-Gharamaleki
Afshin Gharakhani
Abolghasem Jouyban
机构：
[1] Tabriz University of Medical Sciences,Pharmaceutical Analysis Research Center and Faculty of Pharmacy
[2] Tabriz University of Medical Sciences,Biotechnology Research Center
[3] Tabriz University of Medical Sciences,Food and Drug Safety Research Center
[4] Tabriz University of Medical Sciences,Tuberculosis and Lung Diseases Research Center
[5] Tabriz University of Medical Sciences,Liver and Gastrointestinal Diseases Research Center
[6] Tabriz University of Medical Sciences,Immunology Research Center
来源：
Chemical Papers | 2021年 / 75卷
关键词：
Paracetamol; Exhaled breath condensate; Redox reaction; Colorimetry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A redox reaction-based colorimetric method was validated for the qualitative assay and quantitative determination of paracetamol in exhaled breath condensate (EBC). Fe (III) and K3[Fe(CN)6] were used as colorimetric reagents in which paracetamol reduces Fe (III) to Fe (II) due to its reducing property. The produced Fe (II) is chelated with K3[Fe(CN)6] to form prussian blue colored product which can be detected by the naked eye in the range of 0.2–10.0 μg mL−1. The fully validated method was used for the determination of paracetamol in EBC of paracetamol poisoning individuals.
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页码：2901 / 2906
页数：5
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