Synthesis, characterization, and biological activities of some transition metal(II) complexes with the thiosemicarbazone derived from 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one

被引：0

作者：

J. Q. Qu

G. C. Sun

L. F. Wang

L. Qu

机构：

[1] Tianjin University,Department of Chemistry, School of Science

[2] Lanzhou University,State Key Laboratory of Applied Organic Chemistry

[3] Ningxia Academy of Agriculture and Forestry Sciences,undefined

来源：

Chemical Papers | 2006年 / 60卷

关键词：

Suppression Ratio; Molar Conductivity; Fast Atom Bombardment; Thiosemicarbazone; Antitumour Activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A new 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one thiosemicarbazone (HL) was synthesized derived from 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one. Four transition metal(II) complexes of HL have been prepared. Elemental analysis, molar conductivity, IR, UV, 1H NMR spectra, and TG-DTA have been used to characterize these complexes. The complexes have the general formula ML2, where M = Zn, Cu, Co, and Ni. The ligand and its complexes have been studied for their possible biological activity including anti-inflammatory, antibacterial, and antitumour activity in vitro.

引用

页码：214 / 219

页数：5

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