Synthesis, characterization, and biological activities of some transition metal(II) complexes with the thiosemicarbazone derived from 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one

被引：0
|
作者：
J. Q. Qu
G. C. Sun
L. F. Wang
L. Qu
机构：
[1] Tianjin University,Department of Chemistry, School of Science
[2] Lanzhou University,State Key Laboratory of Applied Organic Chemistry
[3] Ningxia Academy of Agriculture and Forestry Sciences,undefined
来源：
Chemical Papers | 2006年 / 60卷
关键词：
Suppression Ratio; Molar Conductivity; Fast Atom Bombardment; Thiosemicarbazone; Antitumour Activity;
D O I：
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中图分类号：
学科分类号：
摘要：
A new 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one thiosemicarbazone (HL) was synthesized derived from 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one. Four transition metal(II) complexes of HL have been prepared. Elemental analysis, molar conductivity, IR, UV, 1H NMR spectra, and TG-DTA have been used to characterize these complexes. The complexes have the general formula ML2, where M = Zn, Cu, Co, and Ni. The ligand and its complexes have been studied for their possible biological activity including anti-inflammatory, antibacterial, and antitumour activity in vitro.
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页码：214 / 219
页数：5
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