Building bridges

被引：0

作者：

Cara E. Brocklehurst

Edward A. Anderson

机构：

[1] Novartis Institutes for Biomedical Research,Global Discovery Chemistry Department

[2] University of Oxford,Department of Chemistry

来源：

Nature Chemistry | 2021年 / 13卷

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D O I：

暂无

中图分类号：

学科分类号：

摘要：

Methods for the synthesis of bicyclo[1.1.1]pentanes (BCPs) typically rely on the release of strain energy, but these routes cannot easily introduce substituents on the BCP bridges. Now, an intramolecular coupling gives access to multi-substituted BCPs, through the synthesis of bridge-substituted bicycloalkyl boronic esters.

引用

页码：928 / 930

页数：2

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