APOBEC3G encapsidation into HIV-1 virions: which RNA is it?

被引:0
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作者
Klaus Strebel
Mohammad A Khan
机构
[1] National Institutes of Health,Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases
来源
Retrovirology | / 5卷
关键词
Antiviral Activity; Cytidine Deaminase; Viral Core; Experimental Model System; Packaging Process;
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摘要
APOBEC3G is a cytidine deaminase with potent antiviral activity. The protein deaminates single-stranded DNA but is known to bind cellular and viral RNAs. There is increasing evidence that RNA binding of APOBEC3G is important for packaging into viral particles. However, there is no consensus yet on the type of RNA involved.
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