APOBEC3G expression and HIV-1 infection in Burkina Faso

被引：1

作者：

Compaore, Tegwinde Rebeca ^{[1
]}

Soubeiga, Serge Theophile ^{[1
]}

Ouattara, Abdoul Karim ^{[1
]}

Tchelougou, Damehan ^{[1
]}

Bisseye, Cyrille ^{[1
]}

Bakouan, Didier Romuald ^{[2
]}

Compaore, Issaka ^{[1
]}

Dembele, Augustine ^{[2
]}

Yonli, Albert Theophane ^{[1
]}

Obiri-Yeboah, Dorcas ^{[3
]}

Djigma, Wendkuuni Florencia ^{[1
]}

Simpore, Jacques ^{[1
]}

机构：

[1] Univ Ouagadougou, Pietro Annigoni Biomol Res Ctr CERBA LABIOGENE, Ouagadougou, Burkina Faso

[2] Permanent Secretary Aids & Sexually Transmitted D, Ouagadougou, Burkina Faso

[3] Univ Cape Coast, Sch Med Sci, Microbiol Dept, Cape Coast, Ghana

来源：

JOURNAL OF PUBLIC HEALTH IN AFRICA | 2018年 / 9卷 / 03期

关键词：

HIV-1; APOBEC3G mRNA; rs8177832; rs35228531; rs6001417; Burkina Faso;

D O I：

10.4081/jphia.2018.907

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

APOBEC3G is a potent inhibitor of HIV-1 replication, and act by deaminating cytidines in uracil on the negative strand of the viral cDNA. In this case-control study, APOBEC3G expression in subjects' naive to HAART infected by HIV-1 and the effect of APOBEC3G polymorphism on its expression were evaluated. The results show that the HIV-1 infected carriers of the G minor alleles of the variant rs8177832 had a higher expression of APOBEC3G mRNA than the controls carriers of the G minor allele. APOBEC3G polymorphisms could play an important role in the modulation of the HIV-1 dissemination.

引用

页码：159 / 161

页数：3

共 50 条

[1] APOBEC3G Variants and Protection against HIV-1 Infection in Burkina Faso
Compaore, Tegwinde Rebeca
Soubeiga, Serge Theophile
Ouattara, Abdoul Karim
Obiri-Yeboah, Dorcas
Tchelougou, Damehan
Maiga, Mamoudou
Assih, Maleki
Bisseye, Cyrille
Bakouan, Didier
Compaore, Issaka Pierre
Dembele, Augustine
Martinson, Jeremy
Simpore, Jacques
[J]. PLOS ONE, 2016, 11 (01):
[2] HBV/HIV co-infection and APOBEC3G polymorphisms in a population from Burkina Faso
Compaore, Tegwinde Rebeca
Diarra, Birama
Assih, Maleki
Obiri-Yeboah, Dorcas
Soubeiga, Serge Theophile
Ouattara, Abdoul Karim
Tchelougou, Damehan
Bisseye, Cyrille
Bakouan, Didier Romuald
Compaore, Issaka Pierre
Dembele, Augustine
Djigma, Wendkuuni Florencia
Simpore, Jacques
[J]. BMC INFECTIOUS DISEASES, 2016, 16
[3] HBV/HIV co-infection and APOBEC3G polymorphisms in a population from Burkina Faso
Tegwinde Rebeca Compaore
Birama Diarra
Maleki Assih
Dorcas Obiri-Yeboah
Serge Theophile Soubeiga
Abdoul Karim Ouattara
Damehan Tchelougou
Cyrille Bisseye
Didier Romuald Bakouan
Issaka Pierre Compaore
Augustine Dembele
Wendkuuni Florencia Djigma
Jacques Simpore
[J]. BMC Infectious Diseases, 16
[4] The Roles of APOBEC3G Complexes in the Incorporation of APOBEC3G into HIV-1
Ma, Jing
Li, Xiaoyu
Xu, Jian
Zhang, Quan
Liu, Zhenlong
Jia, Pingping
Zhou, Jinming
Guo, Fei
You, Xuefu
Yu, Liyan
Zhao, Lixun
Jiang, Jiandong
Cen, Shan
[J]. PLOS ONE, 2013, 8 (10):
[5] APOBEC3G and HIV-1: Strike and counterstrike
Soros V.B.
Greene W.C.
[J]. Current Infectious Disease Reports, 2006, 8 (4) : 317 - 323
[6] APOBEC3G and HIV-1: Strike and counterstrike
Soros V.B.
Greene W.C.
[J]. Current HIV/AIDS Reports, 2007, 4 (1) : 3 - 9
[7] Expression of HIV-1 Vif and Human APOBEC3G with a Bicistronic Vector
Yang Yishu
Sun Xiaona
Liu Di
Wang Xiaoli
Shen Sisi
Li Zelin
Zeng Yi
[J]. MECHANICAL ENGINEERING AND MATERIALS SCIENCE, 2012, 108 : 141 - 145
[8] APOBEC3g mediates innate resistance of Dendritic Cells to HIV-1 infection
Pion, M.
Stalder, R.
Piguet, V
[J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 : 108 - 108
[9] The interaction between HIV-1 Gag and APOBEC3G
Cen, S
Guo, F
Niu, MJ
Saadatmand, J
Deflassieux, J
Kleiman, L
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (32) : 33177 - 33184
[10] Stoichiometry of the antiviral protein APOBEC3G in HIV-1 virions
Xu, Hongzhan
Chertova, Elena
Chen, Jianbo
Ott, David E.
Roser, James D.
Hu, Wei-Shau
Pathak, Vinay K.
[J]. VIROLOGY, 2007, 360 (02) : 247 - 256

← 1 2 3 4 5 →