Assembly of the inner rod determines needle length in the type III secretion injectisome

被引：0

作者：

Thomas C. Marlovits

Tomoko Kubori

María Lara-Tejero

Dennis Thomas

Vinzenz M. Unger

Jorge E. Galán

机构：

[1] Section of Microbial Pathogenesis,Department of Molecular Biophysics and Biochemistry

[2] Yale University School of Medicine,Department of Biochemistry

[3] Boyer Center for Molecular Medicine,undefined

[4] Yale University School of Medicine,undefined

[5] Howard Hughes Medical Institute,undefined

[6] Rosenstiel Basic Medical Sciences Research Center,undefined

[7] Brandeis University,undefined

[8] Research Institute of Molecular Pathology (IMP) and Institute of Molecular Biotechnology,undefined

[9] Austrian Academy of Sciences (IMBA),undefined

[10] 21st Century COE Program,undefined

[11] Combined Program on Microbiology and Immunology,undefined

[12] Osaka University,undefined

来源：

Nature | 2006年 / 441卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The needle complex or ‘injectisome’ that transfers proteins from bacteria to eukaryotic cells is a virulence factor in many bacterial pathogens. A new study of the Salmonella typhimurium injectisome throws light on the mechanism by which ‘needles’ are produced with the appropriate length.

引用

页码：637 / 640

页数：3

共 50 条

[31] A protein secreted by the Salmonella type III secretion system controls needle filament assembly
Kato, Junya
Dey, Supratim
Soto, Jose E.
Butan, Carmen
Wilkinson, Mason C.
De Guzman, Roberto N.
Galan, Jorge E.
ELIFE, 2018, 7
[32] Piericidin A1 Blocks Yersinia Ysc Type III Secretion System Needle Assembly
Morgan, Jessica M.
Duncan, Miles C.
Johnson, Kevin S.
Diepold, Andreas
Lam, Hanh
Dupzyk, Allison J.
Martin, Lexi R.
Wong, Weng Ruh
Armitage, Judith P.
Linington, Roger G.
Auerbuch, Victoria
MSPHERE, 2017, 2 (01):
[33] Molecular characterization and assembly of the needle complex of the Salmonella typhimurium type III protein secretion system
Kubori, T
Sukhan, A
Aizawa, SI
Galán, JE
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (18) : 10225 - 10230
[34] CesL Regulates Type III Secretion Substrate Specificity of the Enteropathogenic E. coli Injectisome
Diaz-Guerrero, Miguel
Gaytan, Meztlli O.
Soto, Eduardo
Espinosa, Norma
Garcia-Gomez, Elizabeth
Marcos-Vilchis, Arely
Andrade, Angel
Gonzalez-Pedrajo, Bertha
MICROORGANISMS, 2021, 9 (05)
[35] Identification of minor inner-membrane components of the Shigella type III secretion system 'needle complex'
Zenk, Sebastian F.
Stabat, David
Hodgkinson, Julie L.
Veenendaal, Andreas K. J.
Johnson, Steven
Blocker, Ariel J.
MICROBIOLOGY-SGM, 2007, 153 : 2405 - 2415
[36] Needle length control and the secretion substrate specificity switch are only loosely coupled in the type III secretion apparatus of Shigella
Shen, Da-Kang
Moriya, Nao
Martinez-Argudo, Isabel
Blocker, Ariel J.
MICROBIOLOGY-SGM, 2012, 158 : 1884 - 1896
[37] An Interaction between the Inner Rod Protein YscI and the Needle Protein YscF Is Required to Assemble the Needle Structure of the Yersinia Type Three Secretion System
Cao, Shi-Yang
Liu, Wan-Bin
Tan, Ya-Fang
Yang, Hui-Ying
Zhang, Ting-Ting
Wang, Tong
Wang, Xiao-Yi
Song, Ya-Jun
Yang, Rui-Fu
Du, Zong-Min
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 292 (13) : 5488 - 5498
[38] Hybrid structural methods to probe atomic features of the Type III Secretion Injectisome of Pathogenic Bacteria
Strynadka, Natalie
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2021, 77 : C21 - C21
[39] Assembly of the bacterial type III secretion machinery
Diepold, Andreas
Wagner, Samuel
FEMS MICROBIOLOGY REVIEWS, 2014, 38 (04) : 802 - 822
[40] Escl: a crucial component of the type III secretion system forms the inner rod structure in enteropathogenic Escherichia coli
Sal-Man, Neta
Deng, Wanyin
Finlay, B. Brett
BIOCHEMICAL JOURNAL, 2012, 442 : 119 - 125

← 1 2 3 4 5 →