Assembly of the inner rod determines needle length in the type III secretion injectisome

被引：0
|
作者：
Thomas C. Marlovits
Tomoko Kubori
María Lara-Tejero
Dennis Thomas
Vinzenz M. Unger
Jorge E. Galán
机构：
[1] Section of Microbial Pathogenesis,Department of Molecular Biophysics and Biochemistry
[2] Yale University School of Medicine,Department of Biochemistry
[3] Boyer Center for Molecular Medicine,undefined
[4] Yale University School of Medicine,undefined
[5] Howard Hughes Medical Institute,undefined
[6] Rosenstiel Basic Medical Sciences Research Center,undefined
[7] Brandeis University,undefined
[8] Research Institute of Molecular Pathology (IMP) and Institute of Molecular Biotechnology,undefined
[9] Austrian Academy of Sciences (IMBA),undefined
[10] 21st Century COE Program,undefined
[11] Combined Program on Microbiology and Immunology,undefined
[12] Osaka University,undefined
来源：
Nature | 2006年 / 441卷
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学科分类号：
摘要：
The needle complex or ‘injectisome’ that transfers proteins from bacteria to eukaryotic cells is a virulence factor in many bacterial pathogens. A new study of the Salmonella typhimurium injectisome throws light on the mechanism by which ‘needles’ are produced with the appropriate length.
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收藏
页码：637 / 640
页数：3
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