Fatal graft-versus-host disease following HLA-mismatched donor lymphocyte infusion

被引:0
|
作者
PJ Amrolia
K Rao
O Slater
A Ramsay
PA Veys
DKH Webb
机构
[1] Great Ormond Street Hospital for Sick Children,Departments of Bone Marrow Transplantation and Pathology
来源
Bone Marrow Transplantation | 2001年 / 28卷
关键词
HLA-mismatched; donor lymphocyte infusion; graft-versus-host disease;
D O I
暂无
中图分类号
学科分类号
摘要
We report the case of a 10-year-old boy with molecular relapse of CML following unrelated donor BMT who developed fatal grade 4 acute GVHD of the gut and liver following one antigen-mismatched donor lymphocyte infusion. Previous experience of donor lymphocyte infusion in the HLA-mismatched setting is reviewed and the role of adoptive immunotherapy in this situation is discussed. Bone Marrow Transplantation (2001) 28, 623–625.
引用
收藏
页码:623 / 625
页数:2
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