Fatal graft-versus-host disease following HLA-mismatched donor lymphocyte infusion

被引：0
|
作者：
PJ Amrolia
K Rao
O Slater
A Ramsay
PA Veys
DKH Webb
机构：
[1] Great Ormond Street Hospital for Sick Children,Departments of Bone Marrow Transplantation and Pathology
来源：
Bone Marrow Transplantation | 2001年 / 28卷
关键词：
HLA-mismatched; donor lymphocyte infusion; graft-versus-host disease;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We report the case of a 10-year-old boy with molecular relapse of CML following unrelated donor BMT who developed fatal grade 4 acute GVHD of the gut and liver following one antigen-mismatched donor lymphocyte infusion. Previous experience of donor lymphocyte infusion in the HLA-mismatched setting is reviewed and the role of adoptive immunotherapy in this situation is discussed. Bone Marrow Transplantation (2001) 28, 623–625.
引用
收藏
页码：623 / 625
页数：2
相关论文
共 50 条
  • [31] Graft-versus-host reactions and the effectiveness of donor lymphocyte infusions
    Huff, CA
    Fuchs, EJ
    Smith, BD
    Blackford, A
    Garrett-Mayer, E
    Brodsky, RA
    Flinn, IW
    Ambinder, RF
    Borrello, IM
    Matsui, WH
    Vogelsang, GB
    Griffin, CA
    Luznik, L
    Jones, RJ
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2006, 12 (04) : 414 - 421
  • [32] The clinicopathologic mucocutaneous spectrum of chronic graft-versus-host disease in a patient receiving a donor T-lymphocyte infusion
    Cappel, Mark
    Snow, John
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2009, 60 (03) : AB76 - AB76
  • [33] Effect of Stem Cell Boost and Donor Lymphocyte Infusion on the Incidence of Graft-Versus-Host Disease at Emory University Hospital
    Yoon, James
    Graiser, Michael
    Garcia, Marco
    Philip, Anisha
    Waller, Edmund K.
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2019, 25 (03)
  • [34] Acute hepatic failure as onset of progressive sclerodermatous chronic graft-versus-host disease after donor lymphocyte infusion
    Skert, C
    Patriarca, F
    Zaja, F
    Tomadini, V
    Fanin, R
    BONE MARROW TRANSPLANTATION, 2005, 35 (05) : 523 - 524
  • [35] HOMOLOGOUS DISEASE - A FATAL GRAFT-VERSUS-HOST REACTION
    TRENTIN, JJ
    ANATOMICAL RECORD, 1959, 133 (02): : 343 - 343
  • [36] Acute hepatic failure as onset of progressive sclerodermatous chronic graft-versus-host disease after donor lymphocyte infusion
    C Skert
    F Patriarca
    F Zaja
    V Tomadini
    R Fanin
    Bone Marrow Transplantation, 2005, 35 : 523 - 524
  • [37] Nonalloreactive T Cells Prevent Donor Lymphocyte Infusion Induced Graft-versus-Host Disease by Controlling Microbial Stimuli
    Li, Hao Wei
    Sachs, Jessica
    Pichardo, Clarimel
    Bronson, Roderick
    Zhao, Guiling
    Sykes, Megan
    JOURNAL OF IMMUNOLOGY, 2012, 189 (12): : 5572 - 5581
  • [38] Induction of chronic graft-versus-host disease in rats through bone marrow transplantation followed by donor lymphocyte infusion
    Hofmeister, N
    Junghanss, C
    Sievert, K
    Terpe, H
    Sekora, A
    Freund, M
    Hartung, G
    Wolff, D
    BONE MARROW TRANSPLANTATION, 2006, 37 : S81 - S82
  • [39] Patient HLA-DP-Specific CD4+ T Cells from HLA-DPB1-Mismatched Donor Lymphocyte Infusion Can Induce Graft-versus-Leukemia Reactivity in the Presence or Absence of Graft-versus-Host Disease
    Rutten, Caroline E.
    van Luxemburg-Heijs, Simone A. P.
    Halkes, Constantijn J. M.
    van Bergen, Cornelis A. M.
    Marijt, Erik W. A.
    Oudshoorn, Machteld
    Griffioen, Marieke
    Falkenburg, J. H. Frederik
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2013, 19 (01) : 40 - 48
  • [40] Donor lymphocyte infusion for treatment of relapse of leukaemia after HLA-mismatched haematopoietic stem cell transplantation
    Huang, X. J.
    BONE MARROW TRANSPLANTATION, 2008, 41 : S415 - S415
12345