Synthesis and antitumor activity of pyrano[4′,3′:4,5]pyrido[2, 3-b]thieno[3,2-d]-1,2,3-triazine and l,2,3-triazino[4′,5′:4, 5|thieno-[2,3-c]isoquinoline derivatives

被引:0
|
作者
Paronikyan E.G. [1 ]
Noravyan A.S. [1 ]
Akopyan Sh.F. [1 ]
Arsenyan F.G. [1 ]
Stepanyan G.M. [1 ]
Garibdzhanyan B.T. [1 ]
机构
[1] Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of Armenia, Yerevan
关键词
Antitumor Activity; Thiophene; Triazine; Tumor Growth Inhibition; Azine;
D O I
10.1007/s11094-006-0112-9
中图分类号
学科分类号
摘要
Methods for the synthesis of new heterosystems of condensed thieno[3,2-d]-1,2,3-triazines on the basis of pyrido[2,3-b]thiophenes have been developed. The antitumor activity of the synthesized compounds was studied and several compounds possessing low toxicity and moderate antitumor activity were found. © 2006 Springer Science+Business Media, Inc.
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页码:293 / 295
页数:2
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