Catalytic Amplification of Electrochemical Signal in Homogeneous Solution Using an Entropy-driven DNA Circuit

被引：0

作者：

Yusuke Kitamura

Keisuke Yoshimura

Ryo Kuramoto

Yousuke Katsuda

Toshihiro Ihara

机构：

[1] Kumamoto University,Division of Materials Science, Faculty of Advanced Science and Technology

来源：

Analytical Sciences | 2021年 / 37卷

关键词：

Nucleic acids; electrochemical biosensor; inclusion complex; ferrocene; cyclodextrin; homogeneous assay; DNA circuit; signal amplification;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The electrochemical signal from ferrocene on a DNA probe was successfully modulated in a homogeneous solution by the template-directed formation and dissociation of an inclusion complex with β-cyclodextrin on another probe. The electrochemical response was amplified by combining with a DNA circuit, in which the target DNA served as a catalyst. This system did not require any modification of a complementary DNA with the ferrocene-modified probe on the electrode surface to separate the bound/free probe for the detection of 200 nM target DNA.

引用

页码：533 / 537

页数：4

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