Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Lusutrombopag, a Novel Thrombopoietin Receptor Agonist, for the Treatment of Thrombocytopenia in Patients with Chronic Liver Disease Undergoing Invasive Procedures

被引：0
|
作者：
Takayuki Katsube
Ryosuke Shimizu
Takahiro Fukuhara
Takeshi Kano
Toshihiro Wajima
机构：
[1] Clinical Pharmacology and Pharmacokinetics,Clinical Research Department
[2] Shionogi & Co.,Project Management Department
[3] Ltd,undefined
[4] Shionogi & Co.,undefined
[5] Ltd,undefined
[6] Shionogi & Co.,undefined
[7] Ltd,undefined
来源：
Clinical Pharmacokinetics | 2019年 / 58卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1469 / 1482
页数：13
相关论文
共 50 条
  • [31] Avatrombopag, a Novel Thrombopoietin Receptor Agonist, Increases Platelet Counts without Increasing Platelet Activation in Patients with Thrombocytopenia Due to Chronic Liver Disease
    Frelinger, Andrew L., III
    Koganov, Elena Smolensky
    Forde, Emma E.
    Carmichael, Sabrina L.
    Michelson, Alan D.
    BLOOD, 2017, 130
  • [32] CONSISTENT EFFICACY OF AVATROMBOPAG OVER PLACEBO IN THE TREATMENT OF THROMBOCYTOPENIA IN PATIENTS WITH CHRONIC LIVER DISEASE UNDERGOING INVASIVE PROCEDURES ACROSS DEMOGRAPHIC
    Vredenburg, Michael
    Reau, Nancy
    Allen, Lee F.
    Aggarwal, Kavita
    Poordad, Fred
    GASTROENTEROLOGY, 2018, 154 (06) : S532 - S532
  • [33] Practice Guidelines of the Central European Hepatologic Collaboration (CEHC) on the Use of Thrombopoietin Receptor Agonists in Patients with Chronic Liver Disease Undergoing Invasive Procedures
    Flisiak, Robert
    Antonov, Krasimir
    Drastich, Pavel
    Jarcuska, Peter
    Maevskaya, Marina
    Makara, Mihaly
    Puljiz, Zeljko
    Stabuc, Borut
    Trifan, Anca
    JOURNAL OF CLINICAL MEDICINE, 2021, 10 (22)
  • [34] Successful Treatment with Thrombopoietin Receptor Agonist in Avoiding Splenectomy for Patients with Chronic Refractory Immune Thrombocytopenia
    Khalafallah, Alhossain
    Rahman, Zafreen
    Ogden, Kath
    Hannan, Terry
    MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES, 2012, 4 (01):
  • [35] COMPARATIVE EFFICACY AND SAFETY OF AVATROMBOPAG VERSUS LUSUTROMBOPAG IN PATIENTS WITH CHRONIC LIVER DISEASE AND SEVERE THROMBOCYTOPENIA UNDERGOING INVASIVE PROCEDURES: A SYSTEMATIC LITERATURE REVIEW AND NETWORK META-ANALYSIS
    Wojciechowski, P.
    Wilson, K.
    Pochopien, M.
    Pustulka, I
    Smela, B.
    Tytula, A.
    Vredenburg, M.
    Nazir, J.
    VALUE IN HEALTH, 2021, 24 : S84 - S84
  • [36] Phase 3 randomised study of avatrombopag, a novel thrombopoietin receptor agonist for the treatment of chronic immune thrombocytopenia
    Jurczak, Wojciech
    Chojnowski, Krzysztof
    Mayer, Jiri
    Krawczyk, Katarzyna
    Jamieson, Brian D.
    Tian, Wei
    Allen, Lee F.
    BRITISH JOURNAL OF HAEMATOLOGY, 2018, 183 (03) : 479 - 490
  • [37] Thrombopoietin-receptor agonists for patients with cirrhosis and severe thrombocytopenia undergoing invasive procedures: A systematic review and meta-analysis
    Rose, P.
    Au, M.
    Woodman, R.
    Tee, D.
    Chinnaratha, M. A.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2020, 35 : 47 - 48
  • [38] Thrombopoietin-receptor agonists in perioperative treatment of patients with chronic liver disease
    Kamran Qureshi
    Alan Bonder
    World Journal of Meta-Analysis, 2020, 8 (03) : 220 - 232
  • [39] COSTS ASSOCIATED WITH THE MANAGEMENT OF CHRONIC LIVER DISEASE-ASSOCIATED SEVERE THROMBOCYTOPENIA IN ADULT PATIENTS UNDERGOING INVASIVE PROCEDURES IN SPAIN
    Gil, A.
    Munoz, R.
    Shepherd, J.
    Zhu, X.
    VALUE IN HEALTH, 2019, 22 : S711 - S711
  • [40] A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Lusutrombopag for Thrombocytopenia in Patients with Chronic Liver Disease Undergoing Elective Invasive Procedures in Japan (L-PLUS 1)
    Izumi, Namiki
    Osaki, Yukio
    Yamamoto, Kazuhide
    Kurokawa, Mineo
    Tanaka, Katsuaki
    Kano, Takeshi
    Fukuhara, Takahiro
    Ochiai, Toshimitsu
    Imawari, Michio
    HEPATOLOGY, 2015, 62 (06) : 1397A - 1398A
12345