Synthesis of the [2H,15N]-labeled antiviral drug “triazavirine”

被引：0
|
作者：
T. S. Shestakova
I. A. Khalymbadzha
S. L. Deev
O. S. Eltsov
V. L. Rusinov
Z. O. Shenkarev
A. S. Arseniev
O. N. Chupakhin
机构：
[1] Ural Federal University,I. Ya. Postovsky Institute of Organic Synthesis
[2] Ural Branch of the Russian Academy of Sciences,M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry
[3] Russian Academy of Sciences,undefined
来源：
Russian Chemical Bulletin | 2011年 / 60卷
关键词：
diazonium salt; azocoupling; [; H,; N]-labeled “triazavirine”; NMR spectra;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Selective methods for the incorporation of stable isotopes 15N and 2H into the structure of antiviral medicine “triazavirine” 1 were developed. The synthesized isotopically modified “triazavirine” 1–2H3,15N3 contained the labeled atoms in both the azole and the azine rings. 13C and 15N NMR spectra of the isotope-containing sample 1–2H3,15N3 were thoroughly analyzed.
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页码：729 / 732
页数：3
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