Reduced menin expression impairs rapamycin effects as evidenced by an increase in mTORC2 signaling and cell migration

被引：0
|
作者：
Masoud Razmara
Azita Monazzam
Britt Skogseid
机构：
[1] Uppsala University,Department of medical sciences, Science for Life Laboratory
来源：
Cell Communication and Signaling | / 16卷
关键词：
MEN1; PNET; PI3K; mTOR; Akt; Rapamycin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Targeted inhibition of mTORC2 prevents osteosarcoma cell migration and promotes apoptosis
    Wang, Xiaokai
    Lai, Pinglin
    Zhang, Zhongmin
    Huang, Minjun
    Wang, Liang
    Yin, Min
    Jin, Dadi
    Zhou, Rongping
    Bai, Xiaochun
    ONCOLOGY REPORTS, 2014, 32 (01) : 382 - 388
  • [22] Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer
    Li, Haiyan
    Lin, Jun
    Wang, Xiaokai
    Yao, Guangyu
    Wang, Liping
    Zheng, Hang
    Yang, Cuilan
    Jia, Chunhong
    Liu, Anling
    Bai, Xiaochun
    BREAST CANCER RESEARCH AND TREATMENT, 2012, 134 (03) : 1057 - 1066
  • [23] Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer
    Haiyan Li
    Jun Lin
    Xiaokai Wang
    Guangyu Yao
    Liping Wang
    Hang Zheng
    Cuilan Yang
    Chunhong Jia
    Anling Liu
    Xiaochun Bai
    Breast Cancer Research and Treatment, 2012, 134 : 1057 - 1066
  • [24] Head and neck cancer stem cell maintenance relies on mTOR signaling, specifically involving the mechanistic target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2)
    Almeida, Luciana O.
    Silva, Luan Cesar
    Emerick, Carolina
    dos Santos, Juliana Amorim
    Castilho, Rogerio M.
    Squarize, Cristiane H.
    ARCHIVES OF ORAL BIOLOGY, 2024, 157
  • [25] mTORC2 regulates PGE2-mediated endothelial cell survival and migration
    Dada, Shirine
    Demartines, Nicolas
    Dormond, Olivier
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 372 (04) : 875 - 879
  • [26] Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses
    Kroczynska, Barbara
    Rafidi, Robert L.
    Majchrzak-Kita, Beata
    Kosciuczuk, Ewa M.
    Blyth, Gavin T.
    Jemielity, Jacek
    Warminska, Zofia
    Saleiro, Diana
    Mehrotra, Swarna
    Arslan, Ahmet Dirim
    Fish, Eleanor N.
    Platanias, Leonidas C.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (05) : 2389 - 2396
  • [27] Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways
    Xu, Chong
    Liu, Chunxiao
    Liu, Lei
    Zhang, Ruijie
    Zhang, Hai
    Chen, Sujuan
    Luo, Yan
    Chen, Long
    Huang, Shile
    NEUROPHARMACOLOGY, 2015, 97 : 35 - 45
  • [28] Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins
    Schreiber, Katherine H.
    Ortiz, Denise
    Academia, Emmeline C.
    Anies, Arieanna C.
    Liao, Chen-Yu
    Kennedy, Brian K.
    AGING CELL, 2015, 14 (02): : 265 - 273
  • [29] mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation
    Zeng, Hu
    Cohen, Sivan
    Guy, Cliff
    Shrestha, Sharad
    Neale, Geoffrey
    Brown, Scott A.
    Cloer, Caryn
    Kishton, Rigel J.
    Gao, Xia
    Youngblood, Ben
    Do, Mytrang
    Li, Ming O.
    Locasale, Jason W.
    Rathmell, Jeffrey C.
    Chi, Hongbo
    IMMUNITY, 2016, 45 (03) : 540 - 554
  • [30] Amino Acids Activate Mammalian Target of Rapamycin Complex 2 (mTORC2) via PI3K/Akt Signaling
    Tato, Irantzu
    Bartrons, Ramon
    Ventura, Francesc
    Luis Rosa, Jose
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (08) : 6128 - 6142
12345