Design, Synthesis and Antitumor Activity Evaluation of Trifluoromethyl-Containing Polysubstituted Pyrimidine Derivatives

被引：0
|
作者：
C. Lingling
W. Hao
Y. Fuqiang
G. Chao
D. Honglin
S. Xiaojie
Z. Yang
Z. Jiaxin
S. Lihong
L. Hongmin
Z. Qiurong
机构：
[1] School of Pharmaceutical Sciences,
[2] Zhengzhou University,undefined
[3] Collaborative Innovation Center of New Drug Research and Safety Evaluation,undefined
[4] State Key Laboratory of Esophageal Cancer Prevention and Treatment,undefined
[5] Key Laboratory of Advanced Drug Preparation Technologie,undefined
[6] Ministry of Education of China,undefined
来源：
Russian Journal of Bioorganic Chemistry | 2023年 / 49卷
关键词：
pyrimidine derivatives; trifluoromethyl; synthesis; antiproliferative activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：86 / 100
页数：14
相关论文
共 50 条
  • [41] Novel pyrimidine derivatives containing an amide moiety: design, synthesis, and antifungal activity
    Wenneng Wu
    Meihang Chen
    Rui Wang
    Haitang Tu
    Maofa Yang
    Guiping Ouyang
    Chemical Papers, 2019, 73 : 719 - 729
  • [42] Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties
    Chai, Bao-Shan
    Liu, Chang-Ling
    Li, Hui-Chao
    He, Xiao-Min
    Luo, Yan-Mei
    Huang, Guang
    Zhang, Hong
    Chang, Jun-Biao
    PEST MANAGEMENT SCIENCE, 2010, 66 (11) : 1208 - 1214
  • [43] Novel pyrimidine derivatives containing an amide moiety: design, synthesis, and antifungal activity
    Wu, Wenneng
    Chen, Meihang
    Wang, Rui
    Tu, Haitang
    Yang, Maofa
    Ouyang, Guiping
    CHEMICAL PAPERS, 2019, 73 (03): : 719 - 729
  • [44] New Potential Antitumor Pyrimidine Derivatives: Synthesis and Cytotoxicity Evaluation
    Masaret, Ghada S.
    POLYCYCLIC AROMATIC COMPOUNDS, 2022, 42 (08) : 5336 - 5351
  • [45] Synthesis and in vitro antitumor activity of novel pyrimidine derivatives of benzothiazoles
    Manjula, S. N.
    Arvind, M. B.
    Vipan, P. K.
    Vijay, R.
    Gopalan, K. N.
    Mallikarjuna, R. C.
    INDIAN JOURNAL OF PHARMACOLOGY, 2008, 40 : 194 - 195
  • [46] Synthesis and Antitumor Activity of 2,4,6-Trisubstituted Novel Quinazoline Derivatives Containing Trifluoromethyl
    Wang Zhengjie
    Dai Honglin
    Si Xiaojie
    Gao Chao
    Liu Limin
    Zhang Luye
    Zhang Yang
    Song Yadan
    Zhao Peirong
    Zheng Jiaxin
    Ke Yu
    Liu Hongmin
    Zhang Qiurong
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2022, 42 (01) : 249 - 256
  • [47] Synthesis, Insecticidal Activity, and Structure-Activity Relationship of Trifluoromethyl-Containing Phthalic Acid Diamide Structures
    Feng, Mei-Li
    Li, Yu-Feng
    Zhu, Hong-Jun
    Zha, Liang
    Xi, Bin-Bin
    Ni, Jue-Ping
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (20) : 10999 - 11006
  • [48] Recent advances in the synthesis of trifluoromethyl-containing heterocyclic compounds via trifluoromethyl building blocks
    Liu, Yaopeng
    Tian, Qingyu
    Ge, Jin
    Wu, Xi
    Li, Zhenghao
    Cheng, Guolin
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 22 (31) : 6246 - 6276
  • [49] Synthesis of trifluoromethyl-containing quinolines from β-(N-arylamino)vinyl trifluoromethyl ketones
    Gerus, I.I.
    Kropachev, A.V.
    Gorbunova, M.G.
    Il'chenko, A.Ya.
    Kukhar', V.P.
    Ukrainskij Khimicheskij Zhurnal, 1993, 59 (04): : 408 - 411
  • [50] RCM-mediated synthesis of trifluoromethyl-containing nitrogen heterocycles
    De Matteis, Valeria
    van Delft, Floris L.
    Jakobi, Harald
    Lindell, Stephen
    Tiebes, Jorgg
    Rutjes, Floris P. J. T.
    JOURNAL OF ORGANIC CHEMISTRY, 2006, 71 (20): : 7527 - 7532
12345