Bone-targeting exosome nanoparticles activate Keap1 / Nrf2 / GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells

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作者
Wenkai Chen
Zongguang Li
Naichun Yu
Linlin Zhang
Hongyu Li
Yongjie Chen
Fengqing Gong
Wenping Lin
Xu He
Siyuan Wang
Yue Wu
Guangrong Ji
机构
[1] Xiamen University,Department of Orthopedic Surgery, Xiang’an Hospital of Xiamen University, School of Medicine
[2] Xiamen University,Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, Xiamen Key Laboratory of Regeneration Medicine, Organ Transplantation Institute of Xiamen University, School of Medicine
[3] Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Department of Spine Surgery, Shenzhen Pingle Orthopedic Hospital
[4] Xiamen University,Department of Orthopedic Surgery, Zhongshan Hospital, School of Medicine
[5] Xiamen University,Department of Pathology, Zhongshan Hospital, School of Medicine
关键词
Homologous targeting; Ferroptosis; Osteosarcoma; Chemotherapy; Nrf2;
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