A case of indometacin-induced acute hepatitis developing into chronic autoimmune hepatitis

被引：0
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作者：
Clara Abraham
John Hart
Susan M Locke
Alfred L Baker
机构：
[1] Section of Digestive Diseases,C Abraham is an Assistant Professor at the Department of Internal Medicine, and at the time of writing was an Assistant Professor in the Section of Gastroenterology and Department of Medicine at The University of Chicago
[2] Yale University School of Medicine,J Hart is a Professor in the Department of Pathology at The University of Chicago
[3] New Haven,undefined
[4] CT,undefined
[5] USA,undefined
[6] IL,undefined
[7] USA.,undefined
[8] IL,undefined
[9] USA.,undefined
[10] SM Locke practices Family Medicine at West Suburban Hospital,undefined
[11] Chicago,undefined
[12] IL,undefined
[13] USA.,undefined
来源：
Nature Clinical Practice Gastroenterology & Hepatology | 2008年 / 5卷
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摘要：
This Case Study describes a 47-year-old woman who was treated with indomethacin for osteoarthritis-related hip pain. Soon after beginning treatment she developed nausea, vomiting, abdominal pain, dark urine and jaundice. Despite discontinuing all medications, her symptoms worsened. Treatment with prednisone 40 mg/day was initially successful, but after tapering (over 18 months) and then discontinuing prednisone her liver chemistry test results worsened and a liver biopsy showed evidence of chronic hepatitis.
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页码：172 / 176
页数：4
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