A case of indometacin-induced acute hepatitis developing into chronic autoimmune hepatitis

被引：0

作者：

Clara Abraham

John Hart

Susan M Locke

Alfred L Baker

机构：

[1] Section of Digestive Diseases,C Abraham is an Assistant Professor at the Department of Internal Medicine, and at the time of writing was an Assistant Professor in the Section of Gastroenterology and Department of Medicine at The University of Chicago

[2] Yale University School of Medicine,J Hart is a Professor in the Department of Pathology at The University of Chicago

[3] New Haven,undefined

[4] CT,undefined

[5] USA,undefined

[6] IL,undefined

[7] USA.,undefined

[8] IL,undefined

[9] USA.,undefined

[10] SM Locke practices Family Medicine at West Suburban Hospital,undefined

[11] Chicago,undefined

[12] IL,undefined

[13] USA.,undefined

来源：

Nature Clinical Practice Gastroenterology & Hepatology | 2008年 / 5卷

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D O I：

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学科分类号：

摘要：

This Case Study describes a 47-year-old woman who was treated with indomethacin for osteoarthritis-related hip pain. Soon after beginning treatment she developed nausea, vomiting, abdominal pain, dark urine and jaundice. Despite discontinuing all medications, her symptoms worsened. Treatment with prednisone 40 mg/day was initially successful, but after tapering (over 18 months) and then discontinuing prednisone her liver chemistry test results worsened and a liver biopsy showed evidence of chronic hepatitis.

引用

页码：172 / 176

页数：4

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