Untranslated regions of mRNAs

被引:0
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作者
Flavio Mignone
Carmela Gissi
Sabino Liuni
Graziano Pesole
机构
[1] Università di Milano,Dipartimento di Fisiologia e Biochimica Generali
[2] Centro di Studio sui Mitocondri e Metabolismo Energetico,undefined
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关键词
Internal Ribosome Entry Site; Stable Secondary Structure; Iron Responsive Element; Internal Ribosome Entry Site Element; Codon Context;
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摘要
Gene expression is finely regulated at the post-transcriptional level. Features of the untranslated regions of mRNAs that control their translation, degradation and localization include stem-loop structures, upstream initiation codons and open reading frames, internal ribosome entry sites and various cis-acting elements that are bound by RNA-binding proteins.
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