Synthesis of 6-Acyl-7-aryl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-5-carboxylic acids and their methyl esters

被引：0
|
作者：
V. L. Gein
L. F. Gein
E. P. Tsyplyakova
O. S. Panova
机构：
[1] Perm State Pharmaceutical Academy,
[2] Perm State Medical Academy,undefined
来源：
Russian Journal of Organic Chemistry | 2007年 / 43卷
关键词：
Dihydro; Aromatic Aldehyde; Ylate; Acetic Acid Lead; Colored Crys;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
6-Acyl-7-aryl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-5-carboxylic acids and methyl 6-acyl-7-aryl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-5-carboxylates were synthesized by fusion of 4-aryl-2,4-dioxobutanoic acids and their methyl esters, respectively, with 1H-tetrazol-5-amine and aromatic aldehydes. The reaction of methyl 2,4-dioxopentanoate with 1H-tetrazol-5-amine and 2-fluorobenzaldehyde in boiling acetic acid gave methyl 6-acetyl-5-hydroxy-7-(2-fluorophenyl)-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine-5-carboxylate.
引用
收藏
页码：1382 / 1386
页数：4
相关论文
共 50 条
  • [31] Synthesis, characterization, quantum chemical studies and electrochemical performance of new 4,7-dihydrotetrazolo[1,5-a]pyrimidine derivatives
    Akbas, Esvet
    Celik, Savas
    Ergan, Erdem
    Levent, Abdulkadir
    JOURNAL OF CHEMICAL SCIENCES, 2019, 131 (04)
  • [32] 5-(4-Bromophenyl)-7-(2,4-dimethoxyphenyl)-4,7-dihydrotetrazolo [1,5-a] pyrimidine
    Ul Haq, Kautsar
    Liawati, Mareta Dewi
    Abdulloh, Abdulloh
    Suwito, Hery
    MOLBANK, 2018, (04)
  • [33] Synthesis, characterization, quantum chemical studies and electrochemical performance of new 4,7-dihydrotetrazolo[1,5-a]pyrimidine derivatives
    Esvet Akbas
    Savas Celik
    Erdem Ergan
    Abdulkadir Levent
    Journal of Chemical Sciences, 2019, 131
  • [34] Synthesis and antimicrobial activity of methyl-7-aryl(heteryl)-6-(2-thienoyl)-4,7- dihydrotetrazolo[1,5-a]pyrimidine-5-carboxylates
    V. L. Gein
    V. V. Mishunin
    E. P. Tsyplyakova
    O. V. Vinokurova
    M. I. Vakhrin
    Pharmaceutical Chemistry Journal, 2009, 43 : 652 - 654
  • [35] The crystal structure of ethyl 7-ethyl-5-methyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate, C10H15N5O2
    Wang, Wenxiang
    Mou, Jiahui
    Sun, Yue
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2023, 238 (01): : 69 - 70
  • [36] IONIC LIQUID-MEDIATED ONE-POT SYNTHESIS OF 5-(TRIFLUOROMETHYL)-4,7-DIHYDROTETRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES
    Li, Tuan-Jie
    Yao, Chang-Sheng
    Yu, Chen-Xia
    Wang, Xiang-Shan
    Tu, Shu-Jiang
    SYNTHETIC COMMUNICATIONS, 2012, 42 (18) : 2728 - 2738
  • [37] High regioselective ultrasonic-assisted synthesis of 2,7-diaryl-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxylic acids
    Chebanov, Valentin A.
    Sakhno, Yana I.
    Desenko, Sergey M.
    ULTRASONICS SONOCHEMISTRY, 2012, 19 (03) : 707 - 709
  • [38] Synthesis and structure of functionalized podands containing 4,7-dihydrotetrazolo[1,5-a]pyrimidine ring. Differently substituted dihydropyrimidine podands
    Filatova, Elena S.
    Fedorova, Olga V.
    Slepukhin, Pavel A.
    Rusinov, Gennady L.
    Charushin, Valery N.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2018, 54 (10) : 971 - 976
  • [39] SYNTHESIS AND TAUTOMERISM OF 5,7-DIARYL-4,7(6,7)-DIHYDROTETRAZOLO[1,5-A]PYRIMIDINES
    ORLOV, VD
    DESENKO, SM
    PIVNENKO, NS
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1988, (11): : 1489 - 1493
  • [40] Synthesis and liquid crystalline properties of the aryl esters of lateral substituted pyrimidine-5-carboxylic acids
    Mikhaleva, MA
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2003, (08): : 1184 - 1189
12345