Determination of ginkgolide A, B, and bilobalide in biloba L. extracts by microdialysis-HPLC

被引：0
|
作者：
Houn-Lin Chiu
Hui-Ya Lin
Thomas Ching-Cherng Yang
机构：
[1] National Kaohsiung Normal University,Department of Chemistry
来源：
Analytical and Bioanalytical Chemistry | 2004年 / 379卷
关键词：
High-performance liquid chromatography; Microdialysis; Ginkgolide A; Ginkgolide B; Bilobalide;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A method has been developed for measuring ginkgolide A, B, and bilobalide in ginkgo biloba L. extracts by using a self-assembled microdialysis device coupled on-line to high-performance liquid chromatography. The optimal conditions for dialysis efficiency and chromatographic analysis were investigated. The results show that the dialysis efficiencies for ginkgolide A, B, and bilobalide are 97.8–100.4%. For the spike concentration of 45 mg L−1, the recoveries of ginkgolide A, B, and bilobalide in ginkgo biloba L. extracts were at 97–100.7% with 3.1–4.7% RSD. The proposed method has therefore been shown to be applicable to the analysis of ginkgolide A, B, and bilobalide in ginkgo biloba L. extracts.
引用
收藏
页码：445 / 448
页数：3
相关论文
共 50 条
  • [21] Differential role of ginkgolide A and bilobalide in CYP3A and CYP2B6 induction by Ginkgo biloba extract in primary cultures of human hepatocytes
    Lau, Aik-Jiang
    Rajaraman, Ganesh
    Baucom, Christie
    Yang, Guixiang
    Chang, Thomas K. H.
    FASEB JOURNAL, 2010, 24
  • [22] Quantitative determination of the iridoid glycosides aucubin and catalpol in Plantago lanceolata L. extracts by HPTLC and HPLC
    Rischer, M
    Adamczyk, M
    Ratz, H
    Hose, S
    Marchesan, M
    Paper, DH
    Franz, G
    Wolf-Heuss, E
    Engel, J
    JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC, 1998, 11 (05) : 374 - 378
  • [23] Antimicrobial Potential of Leaf Extracts of Ginkgo biloba L., Growing in Uttarakhand, India
    Sati, Priyanka
    Pandey, Anita
    Palni, Lok Man S.
    NATIONAL ACADEMY SCIENCE LETTERS-INDIA, 2012, 35 (03): : 201 - 206
  • [24] Antimicrobial Potential of Leaf Extracts of Ginkgo biloba L., Growing in Uttarakhand, India
    Priyanka Sati
    Anita Pandey
    Lok Man S. Palni
    National Academy Science Letters, 2012, 35 : 201 - 206
  • [25] GINKGOLIDE-B PRODUCTION IN CULTURED-CELLS DERIVED FROM GINKGO-BILOBA L LEAVES
    JEON, MH
    SUNG, SH
    HUH, H
    KIM, YC
    PLANT CELL REPORTS, 1995, 14 (08) : 501 - 504
  • [26] Simultaneous determination of ginkgolide A, B, C, bilobalide and rutin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study
    Hu, Bingying
    Sun, Yingying
    Wang, Min
    He, Zhisheng
    Chen, Shanhan
    Qi, Dake
    Ge, Zhen
    Fan, Lingling
    Chen, Jingfang
    Wei, Yang
    ACTA CHROMATOGRAPHICA, 2022, 34 (04) : 386 - 393
  • [27] Distinct role of bilobalide and ginkgolide A in the modulation of rat CYP2B1 and CYP3A23 gene expression by Ginkgo biloba extract in cultured hepatocytes
    Chang, TKH
    Chen, J
    Teng, XW
    FASEB JOURNAL, 2006, 20 (04): : A263 - A263
  • [28] HPLC ANALYSIS OF EXTRACTS OF FRESH PETALS OF PAPAVER RHOEAS L.
    Velickovic, Jasmina M.
    Mitic, Milan N.
    Arsic, Biljana B.
    Paunovic, Dusan D.
    Stojanovic, Branka T.
    Veljkovic, Jovana N.
    Dimitrijevic, Danica S.
    Stevanovic, Slavica D.
    Kostic, Danijela A.
    STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA, 2019, 64 (03): : 239 - 247
  • [29] Distinct role of bilobalide and ginkgolide A in the modulation of rat CYP2B1 and CYP3A23 gene expression by Ginkgo biloba extract in cultured hepatocytes
    Chang, TKH
    Chen, J
    Teng, XW
    DRUG METABOLISM AND DISPOSITION, 2006, 34 (02) : 234 - 242
  • [30] Simultaneous Determination of Nine Flavonoids in Beagle Dog by HPLC with DAD and Application of Ginkgo biloba Extracts on the Pharmacokinetic
    Wu, J.
    Xing, H.
    Tang, D.
    Gao, Y.
    Yin, X.
    Du, Q.
    Jiang, X.
    Yang, D.
    ACTA CHROMATOGRAPHICA, 2012, 24 (04) : 627 - 642
12345