Determination of ginkgolide A, B, and bilobalide in biloba L. extracts by microdialysis-HPLC

被引：0
|
作者：
Houn-Lin Chiu
Hui-Ya Lin
Thomas Ching-Cherng Yang
机构：
[1] National Kaohsiung Normal University,Department of Chemistry
来源：
Analytical and Bioanalytical Chemistry | 2004年 / 379卷
关键词：
High-performance liquid chromatography; Microdialysis; Ginkgolide A; Ginkgolide B; Bilobalide;
D O I：
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学科分类号：
摘要：
A method has been developed for measuring ginkgolide A, B, and bilobalide in ginkgo biloba L. extracts by using a self-assembled microdialysis device coupled on-line to high-performance liquid chromatography. The optimal conditions for dialysis efficiency and chromatographic analysis were investigated. The results show that the dialysis efficiencies for ginkgolide A, B, and bilobalide are 97.8–100.4%. For the spike concentration of 45 mg L−1, the recoveries of ginkgolide A, B, and bilobalide in ginkgo biloba L. extracts were at 97–100.7% with 3.1–4.7% RSD. The proposed method has therefore been shown to be applicable to the analysis of ginkgolide A, B, and bilobalide in ginkgo biloba L. extracts.
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页码：445 / 448
页数：3
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