APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells

被引：0
|
作者：
Mingjue Chen
Tetsuo Mashima
Taichi Oishi
Yukiko Muramatsu
Yosuke Seto
Manabu Takamatsu
Naomi Kawata
Shun Morino
Ayane Nakamura
Saori Inaba
Xunmei Yuan
Kohei Maruyama
Mai Suzuki
Ayana Sato
Haruka Yoshida
Myung-Kyu Jang
Anna Mizutani
Kengo Takeuchi
Kensei Yamaguchi
Fumiyuki Shirai
Satoshi Nagayama
Ryohei Katayama
Hiroyuki Seimiya
机构：
[1] Japanese Foundation for Cancer Research (JFCR),Division of Molecular Biotherapy, Cancer Chemotherapy Center
[2] The University of Tokyo,Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences
[3] Cancer Chemotherapy Center,Division of Experimental Chemotherapy
[4] JFCR,Division of Pathology
[5] The Cancer Institute,Gastroenterological Chemotherapy
[6] JFCR,Graduate School of Pharmaceutical Sciences
[7] Cancer Institute Hospital,Drug Discovery Chemistry Platform Unit
[8] JFCR,Gastroenterological Surgery
[9] Meiji Pharmaceutical University,Department of Surgery
[10] RIKEN Center for Sustainable Resource Science,undefined
[11] Cancer Institute Hospital,undefined
[12] JFCR,undefined
[13] Uji-Tokushukai Medical Center,undefined
来源：
British Journal of Cancer | 2024年 / 130卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：151 / 162
页数：11
相关论文
共 50 条
  • [41] Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells
    Zumwalt, Timothy J.
    Wodarz, Dominik
    Komarova, Natalia L.
    Toden, Shusuke
    Turner, Jacob
    Cardenas, Jacob
    Burn, John
    Chan, Andrew T.
    Boland, C. Richard
    Goel, Ajay
    CANCER PREVENTION RESEARCH, 2017, 10 (03) : 208 - 218
  • [42] PIK3CA mutations predict local recurrence for TME trial rectal cancer patients
    He, Youji
    Vall't Veer, Laura
    Mikolajewska-Hanclich, Izabela
    van Velthuysen, Marie-Louise
    Zeestraten, Eliane
    de Velde, Cornelis
    Marijnen, Corrie
    CANCER RESEARCH, 2009, 69
  • [43] Biochip detection of KRAS, BRAF, and PIK3CA somatic mutations in colorectal cancer patients
    Emelyanova, M. A.
    Amossenko, F. A.
    Semyanikhina, A. V.
    Aliev, V. A.
    Barsukov, Yu. A.
    Lyubchenko, L. N.
    Nasedkina, T. V.
    MOLECULAR BIOLOGY, 2015, 49 (04) : 550 - 559
  • [44] Biochip detection of KRAS, BRAF, and PIK3CA somatic mutations in colorectal cancer patients
    M. A. Emelyanova
    F. A. Amossenko
    A. V. Semyanikhina
    V. A. Aliev
    Yu. A. Barsukov
    L. N. Lyubchenko
    T. V. Nasedkina
    Molecular Biology, 2015, 49 : 550 - 559
  • [45] Targeting β-catenin overcomes MEK inhibition resistance in colon cancer with KRAS and PIK3CA mutations
    Moon, Jai-Hee
    Hong, Seung-Woo
    Kim, Jeong Eun
    Shin, Jae-Sik
    Kim, Jin-Sun
    Jung, Soo-A
    Ha, Seung Hee
    Lee, Seul
    Kim, Joseph
    Lee, Dae Hee
    Park, Yoon Sun
    Kim, Dong Min
    Park, Sang-Soo
    Hong, Jun Ki
    Kim, Do Yeon
    Kim, Eun Ho
    Jung, Joonyee
    Kim, Mi Jin
    Kim, Seung-Mi
    Deming, Dustin A.
    Kim, Kyunggon
    Kim, Tae Won
    Jin, Dong-Hoon
    BRITISH JOURNAL OF CANCER, 2019, 120 (09) : 941 - 951
  • [46] Vitamin D Receptor Expression Is Associated with PIK3CA and KRAS Mutations in Colorectal Cancer
    Kure, Shoko
    Nosho, Katsuhiko
    Baba, Yoshifumi
    Irahara, Natsumi
    Shima, Kaori
    Ng, Kimmie
    Meyerhardt, Jeffrey A.
    Giovannucci, Edward L.
    Fuchs, Charles S.
    Ogino, Shuji
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2009, 18 (10) : 2765 - 2772
  • [47] PIK3CA Mutations Contribute to Acquired Cetuximab Resistance in Patients with Metastatic Colorectal Cancer
    Xu, Jian-Ming
    Wang, Yan
    Wang, You-Liang
    Wang, Yan
    Liu, Tao
    Ni, Ming
    Li, Man-Sheng
    Lin, Li
    Ge, Fei-Jiao
    Gong, Chun
    Gu, Jun-Yan
    Jia, Ru
    Wang, He-Fei
    Chen, Yu-Ling
    Liu, Rong-Rui
    Zhao, Chuan-Hua
    Tan, Zhao-Li
    Jin, Yang
    Zhu, Yun-Ping
    Ogino, Shuji
    Qian, Zhi-Rong
    CLINICAL CANCER RESEARCH, 2017, 23 (16) : 4602 - 4616
  • [48] PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer
    Qiang Wang
    Yan-long Shi
    Kai Zhou
    Li-li Wang
    Ze-xuan Yan
    Yu-lin Liu
    Li-li Xu
    Shi-wei Zhao
    Hui-li Chu
    Ting-ting Shi
    Qing-hua Ma
    Jingwang Bi
    Cell Death & Disease, 9
  • [49] Molecular characteristics of advanced colorectal cancer and multi-hit PIK3CA mutations
    Yasin, Faiza
    Sokol, Ethan
    Vasan, Neil
    Pavlick, Dean C.
    Huang, Richard S. P.
    Pelletier, Maureen
    Levy, Mia Alyce
    Pusztai, Lajos
    Lacy, Jill
    Zhang, Janie Yue
    Ross, Jeffrey S.
    Cecchini, Michael
    ONCOLOGIST, 2024, 29 (12): : 1059 - 1067
  • [50] PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer
    Wang, Qiang
    Shi, Yan-long
    Zhou, Kai
    Wang, Li-li
    Yan, Ze-xuan
    Liu, Yu-lin
    Xu, Li-li
    Zhao, Shi-wei
    chu, Hui-li
    Shi, Ting-ting
    Mai, Qing-hua
    Bi, Jingwang
    CELL DEATH & DISEASE, 2018, 9
12345