APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells

被引：0
|
作者：
Mingjue Chen
Tetsuo Mashima
Taichi Oishi
Yukiko Muramatsu
Yosuke Seto
Manabu Takamatsu
Naomi Kawata
Shun Morino
Ayane Nakamura
Saori Inaba
Xunmei Yuan
Kohei Maruyama
Mai Suzuki
Ayana Sato
Haruka Yoshida
Myung-Kyu Jang
Anna Mizutani
Kengo Takeuchi
Kensei Yamaguchi
Fumiyuki Shirai
Satoshi Nagayama
Ryohei Katayama
Hiroyuki Seimiya
机构：
[1] Japanese Foundation for Cancer Research (JFCR),Division of Molecular Biotherapy, Cancer Chemotherapy Center
[2] The University of Tokyo,Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences
[3] Cancer Chemotherapy Center,Division of Experimental Chemotherapy
[4] JFCR,Division of Pathology
[5] The Cancer Institute,Gastroenterological Chemotherapy
[6] JFCR,Graduate School of Pharmaceutical Sciences
[7] Cancer Institute Hospital,Drug Discovery Chemistry Platform Unit
[8] JFCR,Gastroenterological Surgery
[9] Meiji Pharmaceutical University,Department of Surgery
[10] RIKEN Center for Sustainable Resource Science,undefined
[11] Cancer Institute Hospital,undefined
[12] JFCR,undefined
[13] Uji-Tokushukai Medical Center,undefined
来源：
British Journal of Cancer | 2024年 / 130卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：151 / 162
页数：11
相关论文
共 50 条
  • [31] Mutations of KRAS and PIK3CA as independent predictors of distant metastases in colorectal cancer
    Kunli Zhu
    Hongjiang Yan
    Renben Wang
    Hui Zhu
    Xiangjiao Meng
    Xiaoqing Xu
    Xue Dou
    Dong Chen
    Medical Oncology, 2014, 31
  • [32] PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer
    Manceau, Gilles
    Marisa, Laetitia
    Boige, Valerie
    Duval, Alex
    Gaub, Marie-Pierre
    Milano, Gerard
    Selves, Janick
    Olschwang, Sylviane
    Jooste, Valerie
    le Legrain, Miche
    Lecorre, Delphine
    Guenot, Dominique
    Etienne-Grimaldi, Marie-Christine
    Kirzin, Sylvain
    Martin, Laurent
    Lepage, Come
    Bouvier, Anne-Marie
    Laurent-Puig, Pierre
    CANCER MEDICINE, 2015, 4 (03): : 371 - 382
  • [33] Mutations of KRAS and PIK3CA as independent predictors of distant metastases in colorectal cancer
    Zhu, Kunli
    Yan, Hongjiang
    Wang, Renben
    Zhu, Hui
    Meng, Xiangjiao
    Xu, Xiaoqing
    Dou, Xue
    Chen, Dong
    MEDICAL ONCOLOGY, 2014, 31 (07)
  • [34] Comment on: "Prognostic and Predictive Value of PIK3CA Mutations in Metastatic Colorectal Cancer"
    Han, Wei
    Hu, Yong-wei
    Lu, Wei-jie
    Wang, Hao-nan
    TARGETED ONCOLOGY, 2024, 19 (04) : 661 - 662
  • [35] Analysis of KRAS, NRAS, BRAF, and PIK3CA mutations could predict metastases in colorectal cancer: A preliminary study
    Wojas-Krawczyk, Kamila
    Kalinka-Warzocha, Ewa
    Reszka, Katarzyna
    Nicos, Marcin
    Szumilo, Justyna
    Mandziuk, Slawomir
    Szczepaniak, Katarzyna
    Kupnicka, Dorota
    Lewandowski, Remigiusz
    Milanowski, Janusz
    Krawczyk, Pawel
    ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 28 (01): : 67 - 73
  • [36] Heterogeneity of Epidermal Growth Factor Receptor Status and Mutations of KRAS/PIK3CA in Circulating Tumor Cells of Patients with Colorectal Cancer
    Gasch, Christin
    Bauernhofer, Thomas
    Pichler, Martin
    Langer-Freitag, Sabine
    Reeh, Matthias
    Seifert, Adrian M.
    Mauermann, Oliver
    Izbicki, Jakob R.
    Pantel, Klaus
    Riethdorf, Sabine
    CLINICAL CHEMISTRY, 2013, 59 (01) : 252 - 260
  • [37] Aspirin for colorectal cancer with PIK3CA mutations: the rising of the oldest targeted therapy?
    Amatu, Alessio
    Bencardino, Katia
    Sartore-Bianchi, Andrea
    Siena, Salvatore
    ANNALS OF TRANSLATIONAL MEDICINE, 2013, 1 (02)
  • [38] The role of PIK3CA gene mutations in colorectal cancer and the selection of treatment strategies
    Wang, Haitao
    Tang, Rui
    Jiang, Ling
    Jia, Yingtian
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [39] EVALUATION OF PTEN AND PIK3CA STATUS IN BREAST CANCER FOR PATIENT SELECTION
    Serra, V.
    Rodon, J.
    Aura, C. M.
    Vivancos, A.
    Stemke-Hale, K.
    Hibshoosh, H.
    Wang, Y.
    Ramon Y Cajal, S.
    Tabernero, J.
    Baselga, J.
    ANNALS OF ONCOLOGY, 2012, 23 : 84 - 84
  • [40] PIK3CA mutations do not confer resistance to the EGFR-inhibitor cetuximab in chemorefractory metastatic colorectal cancer
    De Roock, Wendy
    De Schutter, Jef
    Prenen, Hans
    Jacobs, Bart
    Biesmans, Bart
    Claes, Bart
    Lambrechts, Diether
    Van Cutsem, Eric
    Tejpar, Sabine
    CANCER RESEARCH, 2009, 69
12345