Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes

被引：0

作者：

Ophélie Rouxel

Jennifer Da silva

Lucie Beaudoin

Isabelle Nel

Céline Tard

Lucie Cagninacci

Badr Kiaf

Masaya Oshima

Marc Diedisheim

Marion Salou

Alexandra Corbett

Jamie Rossjohn

James McCluskey

Raphael Scharfmann

Manuela Battaglia

Michel Polak

Olivier Lantz

Jacques Beltrand

Agnès Lehuen

机构：

[1] INSERM U1016,Infection and Immunity Program and Department of Biochemistry and Molecular Biology

[2] Institut Cochin,Department of Microbiology and Immunology

[3] Paris,undefined

[4] France,undefined

[5] and Université Paris Descartes,undefined

[6] CNRS,undefined

[7] UMR8104,undefined

[8] Laboratoire d'Excellence INFLAMEX,undefined

[9] Sorbonne Paris Cité,undefined

[10] ,undefined

[11] INSERM U932,undefined

[12] Institut Curie,undefined

[13] Biomedicine Discovery Institute,undefined

[14] Monash University,undefined

[15] ARC Centre of Excellence in Advanced Molecular Imaging,undefined

[16] Monash University,undefined

[17] Institute of Infection and Immunity,undefined

[18] Cardiff University,undefined

[19] Peter Doherty Institute for Infection and Immunity,undefined

[20] University of Melbourne,undefined

[21] Diabetes Research Institute,undefined

[22] IRCCS San Raffaele Scientific Institute,undefined

[23] Milan,undefined

[24] Italy,undefined

[25] and TrialNet Clinical Center,undefined

[26] San Raffaele Hospital,undefined

[27] Service Endocrinologie,undefined

[28] Gynécologie et Diabétologie Pédiatrique,undefined

[29] Hôpital Universitaire Necker Enfants Malades,undefined

[30] Assistance Publique-Hôpitaux de Paris,undefined

[31] Faculté de Médecine Paris Descartes,undefined

[32] Université Sorbonne Paris Cité,undefined

来源：

Nature Immunology | 2017年 / 18卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Type 1 diabetes has a multifactorial etiology. Lehuen and colleagues demonstrate that MAIT cells serve both positive roles and negative roles in type 1 diabetes by maintaining gut integrity and limiting pancreatic inflammation but also directly destroying β-cells.

引用

页码：1321 / 1331

页数：10

共 50 条

[41] Th1 bias of liver mucosal-associated invariant T cells promotes hepatic gluconeogenesis in type 2 diabetes mellitus
Tang, Wenjuan
Ge, Kang
Shen, Lei
Wang, Hongdong
Feng, Wenhuan
Sun, Xitai
Chu, Xuehui
Zhu, Dalong
Yin, Hongli
Bi, Yan
DIABETES-METABOLISM RESEARCH AND REVIEWS, 2023, 39 (04)
[42] Differences in the molecular signatures of mucosal-associated invariant T cells and conventional T cells
Park, Daeui
Kim, Hong Gi
Kim, Miok
Park, Tamina
Ha, Hyung-Ho
Lee, Dae Ho
Park, Kang-Seo
Park, Seong Jun
Lim, Hwan Jung
Lee, Chang Hoon
SCIENTIFIC REPORTS, 2019, 9 (1)
[43] Pathophysiological Roles of Mucosal-Associated Invariant T Cells in the Context of Gut Microbiota-Liver Axis
Gebru, Yoseph Asmelash
Choi, Mi Ran
Raja, Ganesan
Gupta, Haripriya
Sharma, Satya Priya
Choi, Ye Rin
Kim, Hyeong Seop
Yoon, Sang Jun
Kim, Dong Joon
Suk, Ki Tae
MICROORGANISMS, 2021, 9 (02) : 1 - 16
[44] Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1
Emmanuel Treiner
Livine Duban
Seiamak Bahram
Mirjana Radosavljevic
Valerie Wanner
Florence Tilloy
Pierre Affaticati
Susan Gilfillan
Olivier Lantz
Nature, 2003, 422 : 164 - 169
[45] ROLE OF MUCOSAL-ASSOCIATED INVARIANT T (MAIT) CELLS IN A LUPUS MODEL
Murayama, G.
Chiba, A.
Nomura, A.
Amano, H.
Yamaji, K.
Tamura, N.
Miyake, S.
ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 1095 - 1095
[46] Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1
Treiner, E
Duban, L
Bahram, S
Radosavljevic, M
Wanner, V
Tilloy, F
Affaticati, P
Gilfillan, S
Lantz, O
NATURE, 2003, 422 (6928) : 164 - 169
[47] Differences in the molecular signatures of mucosal-associated invariant T cells and conventional T cells
Daeui Park
Hong Gi Kim
Miok Kim
Tamina Park
Hyung-Ho Ha
Dae Ho Lee
Kang-Seo Park
Seong Jun Park
Hwan Jung Lim
Chang Hoon Lee
Scientific Reports, 9
[48] Natural Killer T Cells and Mucosal-Associated invariant T Cells in Lung infections
Trottein, Francois
Paget, Christophe
FRONTIERS IN IMMUNOLOGY, 2018, 9
[49] Evidence for MR1 antigen presentation to mucosal-associated invariant T cells
Huang, SX
Gilfillan, S
Cella, M
Miley, MJ
Lantz, O
Lybarger, L
Fremont, DH
Hansen, TH
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (22) : 21183 - 21193
[50] Perturbation of mucosal-associated invariant T cells and iNKT cells in HIV infection
Juno, Jennifer A.
Phetsouphanh, Chansavath
Klenerman, Paul
Kent, Stephen J.
CURRENT OPINION IN HIV AND AIDS, 2019, 14 (02) : 77 - 84

← 1 2 3 4 5 →