Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer

被引：0

作者：

Jing Shan Lim

Alvaro Ibaseta

Marcus M. Fischer

Belinda Cancilla

Gilbert O’Young

Sandra Cristea

Vincent C. Luca

Dian Yang

Nadine S. Jahchan

Cécile Hamard

Martine Antoine

Marie Wislez

Christina Kong

Jennifer Cain

Yu-Wang Liu

Ann M. Kapoun

K. Christopher Garcia

Timothy Hoey

Christopher L. Murriel

Julien Sage

机构：

[1] Stanford University School of Medicine,Department of Pediatrics

[2] Stanford University School of Medicine,Department of Genetics

[3] OncoMed Pharmaceuticals,Department of Molecular and Cellular Physiology

[4] Inc.,Department of Structural Biology

[5] Stanford University School of Medicine,Department of Pathology

[6] Stanford University School of Medicine,undefined

[7] Howard Hughes Medical Institute,undefined

[8] Stanford University School of Medicine,undefined

[9] Sorbonne Universités,undefined

[10] UPMC Univ Paris 06,undefined

[11] GRC n°04,undefined

[12] AP-HP,undefined

[13] Hôpital Tenon,undefined

[14] Service de Pneumologie,undefined

[15] Stanford University School of Medicine,undefined

来源：

Nature | 2017年 / 545卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

In a mouse model of small-cell lung cancer and in human tumours, activation of the Notch pathway can lead to a cell fate switch of neuroendocrine cells to less proliferative non-neuroendocrine cells, generating intratumoural heterogeneity.

引用

页码：360 / 364

页数：4

共 50 条

[21] SMALL-CELL LUNG-CANCER
DELEIJ, L
BERENDSEN, H
THE, H
EUROPEAN JOURNAL OF RESPIRATORY DISEASES, 1987, 70 : 1 - 4
[22] Treatment of small-cell lung cancer
Mennecier, B
Dansin, E
REVUE DES MALADIES RESPIRATOIRES, 2004, 21 (01) : 171 - 174
[23] Pathology of small-cell lung cancer
K. Junker
Th. Wiethege
K.-M. Müller
Journal of Cancer Research and Clinical Oncology, 2000, 126 : 361 - 368
[24] Radiotherapy for small-cell lung cancer
Laber, DA
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (25): : 2003 - 2003
[25] SMALL-CELL LUNG-CANCER
HINSON, JA
PERRY, MC
CA-A CANCER JOURNAL FOR CLINICIANS, 1993, 43 (04) : 216 - 225
[26] Management of small-cell lung cancer
Thatcher, N
Faivre-Finn, C
Lorigan, P
ANNALS OF ONCOLOGY, 2005, 16 : 235 - 239
[27] Treatment of small-cell lung cancer
Reck, M.
Bohnet, S.
INTERNIST, 2011, 52 (02): : 130 - +
[28] MANAGEMENT OF SMALL-CELL CANCER OF THE LUNG
HANSEN, HH
LANCET, 1992, 339 (8797): : 846 - 849
[29] Surgery for small-cell lung cancer
Al Zreibi, C.
Gibault, L.
Fabre, E.
Le Pimpec-Barthes, F.
REVUE DES MALADIES RESPIRATOIRES, 2021, 38 (08) : 840 - 847
[30] Surgery for Small-Cell Lung Cancer
Anraku, Masaki
Waddell, Thomas K.
SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY, 2006, 18 (03) : 211 - 216

← 1 2 3 4 5 →