A Toll-like receptor 2–integrin β3 complex senses bacterial lipopeptides via vitronectin

被引：0
|
作者：
Gisa Gerold
Khalid Abu Ajaj
Michael Bienert
Hans-Jürgen Laws
Arturo Zychlinsky
Juana L de Diego
机构：
[1] Max Planck Institute for Infection Biology,Department of Cellular Microbiology
[2] Leibniz Institute for Molecular Pharmacology,Department of Peptide Chemistry and Biochemistry
[3] Hematology and Immunology,Department of Pediatric Oncology
[4] Düsseldorf University Hospital,undefined
来源：
Nature Immunology | 2008年 / 9卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Mechanisms facilitating Toll-like receptor 2 (TLR2) ligand recognition are incompletely understood. De Diego and colleagues show that integrin β3 and the serum protein vitronectin are essential for responsiveness to a panel of TLR2 agonists.
引用
收藏
页码：761 / 768
页数：7
相关论文
共 50 条
  • [41] Identification of bacterial sphingophospholipids and their activation of murine macrophages via Toll-like receptor 4
    Fujiwara, N.
    Naka, T.
    Kuwata, H.
    Maeda, S.
    FEBS JOURNAL, 2014, 281 : 199 - 200
  • [42] Bacterial DNA delays neutrophil apoptosis via toll-like receptor-9
    Filep, JG
    Khreiss, T
    József, L
    JOURNAL OF LEUKOCYTE BIOLOGY, 2004, : 61 - 61
  • [43] Salivary and Plasma Levels of Toll-Like Receptor 2 and Toll-Like Receptor 4 in Chronic Periodontitis
    Buduneli, Nurcan
    Ozcaka, Ozgun
    Nalbantsoy, Ayse
    JOURNAL OF PERIODONTOLOGY, 2011, 82 (06) : 878 - 884
  • [44] Comparative fine maps of bovine toll-like receptor 4 and toll-like receptor 2 regions
    Stephen N. White
    Srinivas R. Kata
    James E. Womack
    Mammalian Genome, 2003, 14 : 149 - 155
  • [45] Comparative fine maps of bovine toll-like receptor 4 and toll-like receptor 2 regions
    White, SN
    Kata, SR
    Womack, JE
    MAMMALIAN GENOME, 2003, 14 (02) : 149 - 155
  • [46] β1 INTEGRIN MEDIATES TOLL-LIKE RECEPTOR 2 INDUCED MIGRATION AND INVASION VIA RAC1 ACTIVATION
    McGarry, T.
    Connolly, M.
    McCormick, J.
    Gao, W.
    Veale, D. J.
    Fearon, U.
    ANNALS OF THE RHEUMATIC DISEASES, 2012, 71
  • [47] Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants
    Hanzelmann, Dennis
    Joo, Hwang-Soo
    Franz-Wachtel, Mirita
    Hertlein, Tobias
    Stevanovic, Stefan
    Macek, Boris
    Wolz, Christiane
    Goetz, Friedrich
    Otto, Michael
    Kretschmer, Dorothee
    Peschel, Andreas
    NATURE COMMUNICATIONS, 2016, 7
  • [48] Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants
    Dennis Hanzelmann
    Hwang-Soo Joo
    Mirita Franz-Wachtel
    Tobias Hertlein
    Stefan Stevanovic
    Boris Macek
    Christiane Wolz
    Friedrich Götz
    Michael Otto
    Dorothee Kretschmer
    Andreas Peschel
    Nature Communications, 7
  • [49] Toll-Like Receptors in Innate Immunity: Role of Bacterial Endotoxin and Toll-Like Receptor 4 in Endometrium and Endometriosis
    Khan, Khaleque Newaz
    Kitajima, Michio
    Hiraki, Koichi
    Fujishita, Akira
    Sekine, Ichiro
    Ishimaru, Tadayuki
    Masuzaki, Hideaki
    GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2009, 68 (01) : 40 - 52
  • [50] The role of toll-like receptor 3 in epilepsy
    Benninger, F.
    Gross, A.
    Steiner, I.
    Offen, D.
    Okun, E.
    EUROPEAN JOURNAL OF NEUROLOGY, 2015, 22 : 63 - 63
12345