A Toll-like receptor 2–integrin β3 complex senses bacterial lipopeptides via vitronectin

被引：0
|
作者：
Gisa Gerold
Khalid Abu Ajaj
Michael Bienert
Hans-Jürgen Laws
Arturo Zychlinsky
Juana L de Diego
机构：
[1] Max Planck Institute for Infection Biology,Department of Cellular Microbiology
[2] Leibniz Institute for Molecular Pharmacology,Department of Peptide Chemistry and Biochemistry
[3] Hematology and Immunology,Department of Pediatric Oncology
[4] Düsseldorf University Hospital,undefined
来源：
Nature Immunology | 2008年 / 9卷
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摘要：
Mechanisms facilitating Toll-like receptor 2 (TLR2) ligand recognition are incompletely understood. De Diego and colleagues show that integrin β3 and the serum protein vitronectin are essential for responsiveness to a panel of TLR2 agonists.
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页码：761 / 768
页数：7
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