Interaction of aminoquinolines with unsaturated carboxylic acids. 1. Synthesis of N-quinolyl-β-alanines and their biological activity

被引：0

作者：

Beresnevicius Z.J. ^{[1
]}

Viliunas V. ^{[1
]}

Kantminiene K. ^{[1
]}

机构：

[1] Kaunas University of Technology

来源：

Chemistry of Heterocyclic Compounds | 2000年 / 36卷 / 04期

关键词：

Aminoquinolines; Biological activity; Hydrazides; N-quinolyl-β-alanines;

D O I：

10.1007/BF02269541

中图分类号：

学科分类号：

摘要：

N-Quinolyl-β-alanines, and α-methyl- and β-methyl-N-quinolyl-β-alanines were prepared by reaction of aminoquinolines and acrylic, methacrylic, and crotonic acids. The corresponding hydrazides and benzylidenehydrazides were obtained. 4-Aminoquinoline with unsaturated acids in water gave betaines. The biological activity of sodium salts of β-alanines was investigated.

引用

页码：432 / 438

页数：6

共 50 条

[31] N-hydroxypyridine-2(1H)-thione derivatives of carboxylic acids as activated esters .1. The synthesis of carboxamides.
Barton, DHR
Ferreira, JA
TETRAHEDRON, 1996, 52 (28) : 9347 - 9366
[32] THE SYNTHESIS AND TUBERCULOSTATIC ACTIVITY OF N-ALKYL-N-[6-(DIMETHYLAMINOMETHYLENE)CYCLOHEXENE-1-YL-1]AMIDES OF CARBOXYLIC-ACIDS
KAYUKOVA, LA
DYUSENOVA, ZM
BLEKHMAN, IM
URAZOV, KBS
ERZHANOV, KB
KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1986, 20 (02): : 156 - 158
[33] Synthesis and antimicrobial activity of 10-N-(arylsulpho/aroyl)-7-methyl phenothiazine-1-carboxylic acids
Radadia, VR
Purohit, DM
Patolia, VN
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2005, 15 (01) : 85 - 86
[34] Synthesis and antitumor activity of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids.
Tomita, K
Tsuzuki, Y
Shibamori, K
Kashimoto, S
Ckiba, K
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U1229 - U1229
[35] Synthesis and biological activity of allosteric modulators of GABAB receptors, Part 1.: N-(phenylpropyl)-1-arylethylamines
Kerr, David I. B.
Ong, Jennifer
Perkins, Michael V.
Prager, Rolf H.
Puspawati, Ni Made
AUSTRALIAN JOURNAL OF CHEMISTRY, 2006, 59 (07) : 445 - 456
[36] INFRARED SPECTROSCOPIC INVESTIGATIONS OF ACID-BASE INTERACTIONS IN APROTIC SOLVENTS .1. INTERACTION OF TRI-N-PROPYLAMINE AND SOME CARBOXYLIC ACIDS
SMITH, JW
VITORIA, MC
JOURNAL OF THE CHEMICAL SOCIETY A -INORGANIC PHYSICAL THEORETICAL, 1968, (10): : 2468 - &
[37] INVESTIGATIONS IN PHOSPHINOTHRICINE AND ITS ANALOGS .1. SYNTHESIS AND EQUILIBRIUM CH-ACIDITY OF ESTERS OF N-BENZYLIDENEAMINOALKYL(ARALKYL)CARBOXYLIC ACIDS
MASHCHENKO, NV
MATVEEVA, AG
ODINETS, IL
MATROSOV, EI
PETROV, ES
TEREKHOVA, MI
MATVEEV, AK
MASTRYUKOVA, TA
KABACHNIK, MI
ZHURNAL OBSHCHEI KHIMII, 1988, 58 (09): : 1973 - 1979
[38] PYRROLNITRIN ANALOGS .9. SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 1-TOLYL-3-NITROPHENYL-5-METHYLPYRAZOLE-4-CARBOXYLIC ACIDS AND 1-TOLYL-3-METHYL-5-NITROPHENYLPYRAZOLE-4-CARBOXYLIC ACIDS
CECCHI, L
MELANI, F
PALAZZINO, G
FILACCHIONI, G
PORRETTA, GC
FARMACO-EDIZIONE SCIENTIFICA, 1984, 39 (10): : 888 - 900
[39] PYRROLNITRIN ANALOGS .10. SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 1-CHLOROPHENYL-3-NITROPHENYLPYRAZOLE-4-CARBOXYLIC OR ICHLOROPHENYL-5-NITROPHENYLPYRAZOLE-4-CARBOXYLIC ACIDS
CECCHI, L
MELANI, F
PALAZZINO, G
FILACCHIONI, G
FARMACO-EDIZIONE SCIENTIFICA, 1984, 39 (11): : 953 - 962
[40] UNSATURATED HYDANTOIN DERIVATES .1. SYNTHESIS OF N-METHYL DERIVATES OF DELTA5,ALPHA-HYDANTOINACETIC ACIDS AND 5-HYDANTOINACETIC ACIDS
RUTKOVSK.GV
IVIN, BA
SOCHILIN, EG
TSERETEL.IY
JOURNAL OF GENERAL CHEMISTRY USSR, 1970, 40 (02): : 357 - &

← 1 2 3 4 5 →