Mitochondria can power cells to life and death: Role of mitochondria in apoptosis

被引:0
|
作者
Sah N.K. [1 ]
Taneja T.K. [1 ,3 ]
Hasnain S.E. [1 ,2 ]
机构
[1] Eukaryotic Gene Expression Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi
[2] Laboratory of Molecular & Cellular Biology, CDFD, CDFD Interim Building Complex 7-18, E & F, Nacharam, Hyderabad
[3] Department of Medical Elementology & Toxicology, Jamia Hamdard, Hamdard Nagar, New Delhi
关键词
African Swine Fever; African Swine Fever Virus; Apoptotic Machinery; Growth Factor Withdrawal; Power House;
D O I
10.1007/BF02837908
中图分类号
学科分类号
摘要
Mitochondria serve as power houses of cells but they also possess ‘covered’ knives to kill the cells. A number of intrinsic and extrinsic factors exist which regulate cell killing by mitochondria. Caspases are comparable to a surgeon’s knife, which can be used to sculpt organisms, get rid of wayward, redundant and incorrigibly damaged cells, but can spell doom if not controlled properly. © 2000, Indian Academy of Sciences.
引用
收藏
页码:74 / 84
页数:10
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