Hemodynamics;
Harmonic solution;
Circle of Willis;
Averaging computation;
Pathological analysis;
Cerebral infarction;
D O I:
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摘要:
Hemodynamic indexes will change significantly compared to the normal range of many vascular diseases, therefore it is necessary to establish hemodynamic computation model. Blood circulation is periodically forced huge fluid flow network, the heart is generator of the entire fluid network, based on this hemodynamic characteristics, the circle of Willis’s structure is simplified from the perspective of network and hemodynamics. According to hemodynamic equations and circuit graph theory, models blood flow network of the periodically forced hemodynamic equation, obtains the approximate solution of the harmonic waves form based on averaging computation. We apply this model in the network of the circle of Willis, which may help explain the development processes of cerebral circulation disease. The simulation results show that computing results consistent with the clinical observation of blood flow changes in cerebral infarction.
机构:
Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Surg, Neurosurg Serv, Boston, MA USAHarvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Surg, Neurosurg Serv, Boston, MA USA
Griessenauer, Christoph J.
Ghorbani, Mohammad
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机构:
Iran Univ Med Sci, Firoozgar Hosp, Div Vasc & Endovasc Neurosurg, Tehran, IranHarvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Surg, Neurosurg Serv, Boston, MA USA
机构:
Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R ChinaBeijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R China
Sun, Hao
Li, Bao
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机构:
Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R ChinaBeijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R China
Li, Bao
Zhang, Liyuan
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Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R ChinaBeijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R China
Zhang, Liyuan
Zhang, Yanping
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Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R ChinaBeijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R China
Zhang, Yanping
Liu, Jincheng
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机构:
Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R ChinaBeijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R China
Liu, Jincheng
Huang, Suqin
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Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R ChinaBeijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R China
Huang, Suqin
Xi, Xiaolu
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机构:
Wuhan United Imaging Healthcare Surg Technol Co Lt, Wuhan 430206, Hubei, Peoples R ChinaBeijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R China
Xi, Xiaolu
Liu, Youjun
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Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R ChinaBeijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, 100 Pingleyuan, Beijing, Peoples R China
机构:
Univ Sri Jayewardenepura, Fac Med Sci, Interdisciplinary Ctr Innovat Biotechnol & Neuros, Genet Diagnost & Res Lab, Nugegoda, Sri Lanka
Univ Sri Jayewardenepura, Fac Med Sci, Human Brain Tissue & DNA Repository, Dept Anat, Nugegoda, Sri Lanka
EURON European Grad Sch Neurosci, Maastricht, NetherlandsUniv Sri Jayewardenepura, Fac Med Sci, Interdisciplinary Ctr Innovat Biotechnol & Neuros, Genet Diagnost & Res Lab, Nugegoda, Sri Lanka
Wijesinghe, P.
Steinbusch, H. W. M.
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机构:
Univ Maastricht, Fac Hlth Med & Life Sci, Dept Translat Neurosci, Maastricht, Netherlands
EURON European Grad Sch Neurosci, Maastricht, NetherlandsUniv Sri Jayewardenepura, Fac Med Sci, Interdisciplinary Ctr Innovat Biotechnol & Neuros, Genet Diagnost & Res Lab, Nugegoda, Sri Lanka
Steinbusch, H. W. M.
Shankar, S. K.
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机构:
Natl Inst Mental Hlth & Neurosci NIMHANS, Dept Neuropathol, Bangalore, Karnataka, IndiaUniv Sri Jayewardenepura, Fac Med Sci, Interdisciplinary Ctr Innovat Biotechnol & Neuros, Genet Diagnost & Res Lab, Nugegoda, Sri Lanka
Shankar, S. K.
Yasha, T. C.
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机构:
Natl Inst Mental Hlth & Neurosci NIMHANS, Dept Neuropathol, Bangalore, Karnataka, IndiaUniv Sri Jayewardenepura, Fac Med Sci, Interdisciplinary Ctr Innovat Biotechnol & Neuros, Genet Diagnost & Res Lab, Nugegoda, Sri Lanka
Yasha, T. C.
De Silva, K. R. D.
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机构:
Univ Sri Jayewardenepura, Fac Med Sci, Interdisciplinary Ctr Innovat Biotechnol & Neuros, Genet Diagnost & Res Lab, Nugegoda, Sri Lanka
Univ Sri Jayewardenepura, Fac Med Sci, Human Brain Tissue & DNA Repository, Dept Anat, Nugegoda, Sri Lanka
EURON European Grad Sch Neurosci, Maastricht, NetherlandsUniv Sri Jayewardenepura, Fac Med Sci, Interdisciplinary Ctr Innovat Biotechnol & Neuros, Genet Diagnost & Res Lab, Nugegoda, Sri Lanka