Hemodynamic Solution Computation and Pathological Analysis in the Circle of Willis

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作者
Jinxue Sui
Li Yang
Xinguang Zhang
Hongzhi Shi
Ya Hu
机构
[1] Shandong Technology and Business University,School of Information and Electronic Engineering
[2] Key Laboratory of Sensing Technology and Control in Universities of Shandong,School of Mathematics and Information Sciences
[3] Shandong Co-Innovation Center of Future Intelligent Computing,undefined
[4] Yantai University,undefined
[5] Yantaishan Hospital,undefined
[6] University of Western Australia,undefined
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关键词
Hemodynamics; Harmonic solution; Circle of Willis; Averaging computation; Pathological analysis; Cerebral infarction;
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摘要
Hemodynamic indexes will change significantly compared to the normal range of many vascular diseases, therefore it is necessary to establish hemodynamic computation model. Blood circulation is periodically forced huge fluid flow network, the heart is generator of the entire fluid network, based on this hemodynamic characteristics, the circle of Willis’s structure is simplified from the perspective of network and hemodynamics. According to hemodynamic equations and circuit graph theory, models blood flow network of the periodically forced hemodynamic equation, obtains the approximate solution of the harmonic waves form based on averaging computation. We apply this model in the network of the circle of Willis, which may help explain the development processes of cerebral circulation disease. The simulation results show that computing results consistent with the clinical observation of blood flow changes in cerebral infarction.
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