Rewiring innate and adaptive immunity with TLR9 agonist to treat osteosarcoma

被引：0
|
作者：
Caterina Cascini
Chiara Ratti
Laura Botti
Beatrice Parma
Valeria Cancila
Adriana Salvaggio
Cristina Meazza
Claudio Tripodo
Mario P. Colombo
Claudia Chiodoni
机构：
[1] Fondazione IRCCS Istituto Nazionale Dei Tumori,Department of Experimental Oncology, Molecular Immunology Unit
[2] University of Palermo School of Medicine,Department of Health Science, Tumor Immunology Unit
[3] Fondazione IRCCS Istituto Nazionale Dei Tumori,Pediatric Oncology
[4] IFOM,undefined
[5] FIRC Institute of Molecular Oncology,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 42卷
关键词：
Osteosarcoma; Immunomodulation; Lymphocyte activation; Macrophages; TLR9; Mouse models;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Chicken TLR21 Is an Innate CpG DNA Receptor Distinct from Mammalian TLR9
    Keestra, A. Marijke
    de Zoete, Marcel R.
    Bouwman, Lieneke I.
    van Putten, Jos P. M.
    JOURNAL OF IMMUNOLOGY, 2010, 185 (01): : 460 - 467
  • [42] Activity of a Sting and a TLR9 Agonist As an "in Situ Therapeutic Vaccination" Against Lymphomas
    Sallets, Adrienne
    Barfi, Idit Sagiv
    Levy, Ron
    BLOOD, 2016, 128 (22)
  • [43] Evaluation of the complexity of the immune response to CMP-001, a TLR9 agonist
    Sabree, Shakoora
    Voigt, Andrew
    Rogers, Laura
    Blackwell, Sue
    Lemke-Miltner, Caitlin
    Weiner, George J.
    CANCER RESEARCH, 2020, 80 (16)
  • [44] Addition of TLR9 agonist immunotherapy to radiation improves systemic antitumor activity
    Younes, Ahmed, I
    Barsoumian, Hampartsoum B.
    Sezen, Duygu
    Verma, Vivek
    Patel, Roshal
    Wasley, Mark
    Hu, Yun
    Dunn, Joe D.
    He, Kewen
    Chen, Dawei
    Menon, Hari
    Masrorpour, Fatemeh
    Gu, Meidi
    Yang, Liangpeng
    Puebla-Osorio, Nahum
    Cortez, Maria Angelica
    Welsh, James W.
    TRANSLATIONAL ONCOLOGY, 2021, 14 (02):
  • [45] Coadministration of Telomerase Genetic Vaccine and a Novel TLR9 Agonist in Nonhuman Primates
    Dharmapuri, Sridhar
    Peruzzi, Daniela
    Mennuni, Carmela
    Calvaruso, Francesco
    Giampaoli, Saverio
    Barbato, Gaetano
    Kandimalla, Ekambar R.
    Agrawal, Sudhir
    Scarselli, Elisa
    Mesiti, Giuseppe
    Ciliberto, Gennaro
    La Monica, Nicola
    Aurisicchio, Luigi
    MOLECULAR THERAPY, 2009, 17 (10) : 1804 - 1813
  • [46] Cobitolimod Toll-like receptor 9 (TLR9) agonist Treatment of ulcerative colitis
    Cole, P.
    DRUGS OF THE FUTURE, 2017, 42 (06) : 323 - 326
  • [47] Epithelial TLR9 upregulation by respiratory viruses impairs pulmonary antibacterial immunity
    Rich, Helen Eva Adams
    Bhutia, Simran
    Martinez-Colon, Giovanny
    Warheit-Niemi, Helen
    Bame, Monica
    Moore, Bethany
    JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [48] TLR9 and MyD88 Are Crucial for the Development of Protective Immunity to Malaria
    Gowda, Nagaraj M.
    Wu, Xianzhu
    Gowda, D. Channe
    JOURNAL OF IMMUNOLOGY, 2012, 188 (10): : 5073 - 5085
  • [49] Discovery of new and diverse TLR9 receptor antagonists for regulating innate immune reactions
    Goldblum, Amiram
    Burger-Kentischer, Anke
    Mattes, Angela
    Zatsepin, Maria
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [50] TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis
    Liese, Jan
    Schleicher, Ulrike
    Bogdan, Christian
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2007, 37 (12) : 3424 - 3434
12345