Rewiring innate and adaptive immunity with TLR9 agonist to treat osteosarcoma

被引：0
|
作者：
Caterina Cascini
Chiara Ratti
Laura Botti
Beatrice Parma
Valeria Cancila
Adriana Salvaggio
Cristina Meazza
Claudio Tripodo
Mario P. Colombo
Claudia Chiodoni
机构：
[1] Fondazione IRCCS Istituto Nazionale Dei Tumori,Department of Experimental Oncology, Molecular Immunology Unit
[2] University of Palermo School of Medicine,Department of Health Science, Tumor Immunology Unit
[3] Fondazione IRCCS Istituto Nazionale Dei Tumori,Pediatric Oncology
[4] IFOM,undefined
[5] FIRC Institute of Molecular Oncology,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 42卷
关键词：
Osteosarcoma; Immunomodulation; Lymphocyte activation; Macrophages; TLR9; Mouse models;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] A TLR9 agonist enhances the anti-tumor immunity of peptide and lipopeptide vaccines via different mechanisms
    Song, Ying-Chyi
    Liu, Shih-Jen
    SCIENTIFIC REPORTS, 2015, 5
  • [32] Hemozoin: Malaria's "Built-In" Adjuvant and TLR9 Agonist
    Wagner, Hermann
    CELL HOST & MICROBE, 2010, 7 (01) : 5 - 6
  • [33] TLR9 agonist SNA-induced innate and adaptive immune responses in tumor microenvironment enhance checkpoint inhibitor antitumor activity in mouse tumor models
    Nallagatla, SubbaRao
    Anderson, Bart R.
    Kang, Richard
    Kandimalla, Ekambar R.
    CANCER RESEARCH, 2018, 78 (13)
  • [34] A TLR9 agonist enhances therapeutic effects of telomerase genetic vaccine
    Conforti, Antonella
    Cipriani, Barbara
    Peruzzi, Daniela
    Dharmapuri, Sridhar
    Kandimalla, Ekambar R.
    Agrawal, Sudhir
    Mori, Federica
    Ciliberto, Gennaro
    La Monica, Nicola
    Aurisicchio, Luigi
    VACCINE, 2010, 28 (20) : 3522 - 3530
  • [35] Radiation potentiates systemic anti-tumor immunity unleashed by a novel TLR9 agonist (SD-101)
    Pilones, Karsten
    Kraynak, Jeffrey
    Demaria, Sandra
    Golden, Encouse
    Formenti, Silvia
    CANCER RESEARCH, 2016, 76
  • [36] Radiation Improves Systemic Anti-Tumor Immunity Unleashed by a Novel TLR9 Agonist (SD-101)
    Pilones, K. A.
    Guiducci, C.
    Demaria, S.
    Formenti, S.
    Golden, E.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2016, 96 (02): : S87 - S87
  • [37] TLR9 SIGNALING IN FIBROBLASTIC RETICULAR CELLS REGULATES PERITONEAL IMMUNITY
    Li, Yiming
    Xu, Li
    Chen, Tianmeng
    Loughran, Patricia
    Liao, Hong
    Hoffman, Rosemary
    Billiar, Timothy R.
    Deng, Meihong
    SHOCK, 2019, 51 (06): : 53 - 53
  • [38] TLR9 signaling in fibroblastic reticular cells regulates peritoneal immunity
    Xu, Li
    Li, Yiming
    Yang, Chenxuan
    Loughran, Patricia
    Liao, Hong
    Hoffman, Rosemary
    Billiar, Timothy R.
    Deng, Meihong
    JOURNAL OF CLINICAL INVESTIGATION, 2019, 129 (09): : 3657 - 3669
  • [39] TLR9 signaling in fibroblastic reticular cells regulates peritoneal immunity
    Xu, L.
    Li, Y.
    Yang, C.
    Loughran, P.
    Billiar, T.
    Deng, M.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 69 - 69
  • [40] The role of DNA sensing and innate immune receptor TLR9 in otitis media
    Leichtle, Anke
    Hernandez, Michelle
    Lee, Jasmine
    Pak, Kwang
    Webster, Nicholas J.
    Wollenberg, Barbara
    Wasserman, Stephen I.
    Ryan, Allen F.
    INNATE IMMUNITY, 2012, 18 (01) : 3 - 13
12345