Antianemic activity of polymetallocomplexes of pectin polysaccharides with Fe2+, Co2+, and Cu2+ with different ratios of D metals

被引：0
|
作者：
Vyshtakalyuk A.B. [1 ,2 ]
Karaseva A.N. [1 ,2 ]
Karlin V.V. [1 ,2 ]
Minzanova S.T. [1 ,2 ]
Mironov V.F. [1 ,2 ]
Konovalov A.I. [1 ,2 ]
机构：
[1] A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan
[2] Scientific Center, Russian Academy of Sciences, Kazan'
来源：
Pharmaceutical Chemistry Journal | 2008年 / 42卷 / 6期
基金：
俄罗斯基础研究基金会;
关键词：
Pectin; Hemoglobin Concentration; Erythrocyte Count; Daily Weight Gain; Pectin Polysaccharide;
D O I：
10.1007/s11094-008-0130-x
中图分类号：
学科分类号：
摘要：
The antianemic activity of water-soluble polymetallocomplexes of pectin polysaccharides containing d metal ions - Fe2+, Co2+, and Cu2+ - at different ratios was studied in laboratory rats. The results showed that complexes had marked stimulatory effects on hematopoietic processes, with increases in hemoglobin concentrations and erythrocyte counts, along with intensification of the recovery of hematological parameters after anemia induced by hemorrhage. The highest level of activity on hematological measures was obtained with the polymetallocomplex containing Fe2+, Co2+, and Cu2+ ions at a ratio close to 1:1:1. © 2008 Springer Science+Business Media, Inc.
引用
收藏
页码：309 / 312
页数：3
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