Cyclocondensations of 3-alkylpyrazol-5-amines with 3-arylprop-2-enals and cyclic 1,3-diketones

被引:0
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作者
N. I. Zemlyanaya
V. V. Borodina
V. I. Musatov
S. V. Shishkina
D. S. Sofronov
V. V. Lipson
机构
[1] National Academy of Medical Sciences of Ukraine,Danilevskii Institute of Endocrinous Pathology Problems
[2] National Academy of Sciences of Ukraine,Institute for Single Crystals
[3] Karazin Kharkiv National University,undefined
来源
Russian Journal of Organic Chemistry | 2017年 / 53卷
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摘要
Domino reactions of 3-alkylpyrazol-5-amines with 3-arylprop-2-enals and cyclic 1,3-diketones regioselectively afforded pyrazolo[3,4-b]pyridine derivatives. The alkylation and acylation of the synthesized compounds were studied using 3,7,7-trimethyl-4-[(E)-2-phenylethenyl]-2,4,6,7,8,9-hexahydro-5H-pyrazolo-[3,4-b]quinolin-5-one as model.
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页码:582 / 591
页数:9
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