The epigenetic landscape of Alzheimer's disease

被引:0
|
作者
Jenny Lord
Carlos Cruchaga
机构
[1] Washington University School of Medicine,Jenny Lord and Carlos Cruchaga are in the Department of Psychiatry
[2] St. Louis,undefined
[3] Missouri,undefined
[4] USA.,undefined
[5] Carlos Cruchaga is in the Hope Center Program on Protein Aggregation and Neurodegeneration,undefined
[6] Washington University School of Medicine,undefined
[7] St. Louis,undefined
[8] Missouri,undefined
[9] USA.,undefined
来源
Nature Neuroscience | 2014年 / 17卷
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摘要
Two independent epigenome-wide association studies of Alzheimer's disease cohorts have identified overlapping methylation signals in four loci, ANK1, RPL13, RHBDF2 and CDH23, not previously associated with Alzheimer's disease. These studies also suggest that epigenetic changes contribute more to Alzheimer's disease than expected.
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页码:1138 / 1140
页数:2
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