Synthesis of halogenated derivatives of thymol and their antimicrobial activities

被引：0
|
作者：
Ranjeet Kaur
Mahendra P. Darokar
Sunil Kumar Chattopadhyay
Vinay Krishna
Ateeque Ahmad
机构：
[1] Central Institute of Medicinal and Aromatic Plants (CSIR),Process Chemistry and Chemical Engineering Department
[2] Central Institute of Medicinal and Aromatic Plants (CSIR),Genetic Resource Biotechnology Department
来源：
Medicinal Chemistry Research | 2014年 / 23卷
关键词：
Thymol derivatives; -Halosuccinimide; Antibacterial activity; Antifungal activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In order to test the antibacterial and antifungal activities of different halogenated thymol derivatives, thymol has been converted into chlorothymol, dichlorothymol with N-chlorosuccinimide; monobromothymol, dibromothymol with N-bromosuccinimide; O-methylated iodothymol with ceric ammonium nitrate and iodine from methylated thymol. Among the different derivatives tested, 4-chlorothymol was found to be most active against Staphylococcus aureus and Staphylococcusepidermis at a concentration of 12.5 and 25 ppm, respectively. Also it was tested to be active against Candida albicans (AI).
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页码：2212 / 2217
页数：5
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